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Towards quality assurance and quality control in untargeted metabolomics studies
| Publication available at: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443086/ |
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| Title: | Towards quality assurance and quality control in untargeted metabolomics studies |
| Authors: | Beger, RD Dunn, WB Bandukwala, A Bethan, B Broadhurst, D Clish, CB Dasari, S Derr, L Evans, A Fischer, S Flynn, T Hartung, T Herrington, D Higashi, R Hsu, P-C Jones, C Kachman, M Karuso, H Kruppa, G Lippa, K Maruvada, P Mosley, J Ntai, I O'Donovan, C Playdon, M Raftery, D Shaughnessy, D Souza, A Spaeder, T Spalholz, B Tayyari, F Ubhi, B Verma, M Walk, T Wilson, I Witkin, K Bearden, DW Zanetti, KA |
| Item Type: | Journal Article |
| Abstract: | We describe here the agreed upon first development steps and priority objectives of a community engagement effort to address current challenges in quality assurance (QA) and quality control (QC) in untargeted metabolomic studies. This has included (1) a QA and QC questionnaire responded to by the metabolomics community in 2015 which recommended education of the metabolomics community, development of appropriate standard reference materials and providing incentives for laboratories to apply QA and QC; (2) a 2-day ‘Think Tank on Quality Assurance and Quality Control for Untargeted Metabolomic Studies’ held at the National Cancer Institute’s Shady Grove Campus and (3) establishment of the Metabolomics Quality Assurance and Quality Control Consortium (mQACC) to drive forward developments in a coordinated manner. |
| Issue Date: | 1-Jan-2019 |
| Date of Acceptance: | 5-Dec-2018 |
| URI: | http://hdl.handle.net/10044/1/82413 |
| DOI: | 10.1007/s11306-018-1460-7 |
| ISSN: | 1573-3882 |
| Publisher: | Springer Verlag |
| Start Page: | 1 |
| End Page: | 5 |
| Journal / Book Title: | Metabolomics |
| Volume: | 15 |
| Issue: | 1 |
| Copyright Statement: | © Springer Science+Business Media, LLC, part of Springer Nature 2019 |
| Keywords: | Science & Technology Life Sciences & Biomedicine Endocrinology & Metabolism Quality assurance (QA) Quality control (QC) Community engagement Test materials Reporting metrics Community engagement Quality assurance (QA) Quality control (QC) Reporting metrics Test materials Humans Laboratories Metabolomics Quality Control Quality Improvement Humans Quality Control Laboratories Metabolomics Quality Improvement Science & Technology Life Sciences & Biomedicine Endocrinology & Metabolism Quality assurance (QA) Quality control (QC) Community engagement Test materials Reporting metrics Analytical Chemistry 0301 Analytical Chemistry 0601 Biochemistry and Cell Biology 1103 Clinical Sciences |
| Publication Status: | Published |
| Open Access location: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443086/ |
| Article Number: | ARTN 4 |
| Online Publication Date: | 2019-01-03 |
| Appears in Collections: | Department of Surgery and Cancer Faculty of Medicine |