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Evaluation of prognostic risk models for postoperative pulmonary complications in adult patients undergoing major abdominal surgery: a systematic review and international external validation cohort study
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 PIIS2589750022000693.pdf | Published version | 882.01 kB | Adobe PDF | View/Open |
| Title: | Evaluation of prognostic risk models for postoperative pulmonary complications in adult patients undergoing major abdominal surgery: a systematic review and international external validation cohort study |
| Authors: | Kouli, O Murray, V Bhatia, S Cambridge, WA Kawka, M Shafi, S Knight, SR Kamarajah, SK McLean, KA Glasbey, JC Khaw, RA Ahmed, W Akhbari, M Baker, D Borakati, A Mills, E Thavayogan, R Yasin, I Raubenheimer, K Ridley, W Sarrami, M Zhang, G Egoroff, N Pockney, P Richards, T Bhangu, A Creagh-Brown, B Edwards, M Harrison, EM Lee, M Nepogodiev, D Pinkney, T Pearse, R Smart, N Vohra, R Sohrabi, C Jamieson, A Nguyen, M Rahman, A English, C Tincknell, L Kakodkar, P Kwek, I Punjabi, N Burns, J Varghese, S Erotocritou, M McGuckin, S Vayalapra, S Dominguez, E Moneim, J Salehi, M Tan, HL Yoong, A Zhu, L Seale, B Nowinka, Z Patel, N Chrisp, B Harris, J Maleyko, I Muneeb, F Gough, M James, CE Skan, O Chowdhury, A Rebuffa, N Khan, H Down, B Fatimah Hussain, Q Adams, M Bailey, A Cullen, G Fu, YXJ McClement, B Taylor, A Aitken, S Bachelet, B Brousse de Gersigny, J Chang, C Khehra, B Lahoud, N Lee Solano, M Louca, M Rozenbroek, P Rozitis, E Agbinya, N Anderson, E Arwi, G Barry, I Batchelor, C Chong, T Choo, LY Clark, L Daniels, M Goh, J Handa, A Hanna, J Huynh, L Jeon, A Kanbour, A Lee, A Lee, J Lee, T Leigh, J Ly, D McGregor, F Moss, J Nejatian, M O'Loughlin, E Ramos, I Sanchez, B Shrivathsa, A Sincari, A Sobhi, S Swart, R Trimboli, J Wignall, P Bourke, E Chong, A Clayton, S Dawson, A Hardy, E Iqbal, R Le, L Mao, S Marinelli, I Metcalfe, H Panicker, D R, HH Ridgway, S Tan, HH Thong, S Van, M Woon, S Woon-Shoo-Tong, XS Yu, S Ali, K Chee, J Chiu, C Chow, YW Duller, A Nagappan, P Ng, S Selvanathan, M Sheridan, C Temple, M Do, JE Dudi-Venkata, NN Humphries, E Li, L Mansour, LT Massy-Westropp, C Fang, B Farbood, K Hong, H Huang, Y Joan, M Koh, C Liu, YHA Mahajan, T Muller, E Park, R Tanudisastro, M Wu, JJG Chopra, P Giang, S Radcliffe, S Thach, P Wallace, D Wilkes, A Chinta, SH Li, J Phan, J Rahman, F Segaran, A Shannon, J Zhang, M Adams, N Bonte, A Choudhry, A Colterjohn, N Croyle, JA Donohue, J Feighery, A Keane, A McNamara, D Munir, K Roche, D Sabnani, R Seligman, D Sharma, S Stickney, Z Suchy, H Tan, R Yordi, S Ahmed, I Aranha, M El Sabawy, D Garwood, P Harnett, M Holohan, R Howard, R Kayyal, Y Krakoski, N Lupo, M McGilberry, W Nepon, H Scoleri, Y Urbina, C Ahmad Fuad, MF Ahmed, O Jaswantlal, D Kelly, E Khan, MHT Naidu, D Neo, WX O'Neill, R Sugrue, M Abbas, JD Abdul-Fattah, S Azlan, A Barry, K Idris, NS Kaka, N Mc Dermott, D Mohammad Nasir, MN Mozo, M Rehal, A Shaikh Yousef, M Wong, RH Curran, E Gardner, M Hogan, A Julka, R Lasser, G Ní Chorráin, N Ting, J Browne, R George, S Janjua, Z Leung Shing, V Megally, M Murphy, S Ravenscroft, L Vedadi, A Vyas, V Bryan, A Sheikh, A Ubhi, J Vannelli, K Vawda, A Adeusi, L Doherty, C Fitzgerald, C Gallagher, H Gill, P Hamza, H Hogan, M Kelly, S Larry, J Lynch, P Mazeni, NA O'Connell, R O'Loghlin, R Singh, K Abbas Syed, R Ali, A Alkandari, B Arnold, A Arora, E Azam, R Breathnach, C Cheema, J Compton, M Curran, S Elliott, JA Jayasamraj, O Mohammed, N Noone, A Pal, A Pandey, S Quinn, P Sheridan, R Siew, L Tan, EP Tio, SW Toh, VTR Walsh, M Yap, C Yassa, J Young, T Agarwal, N Almoosawy, SA Bowen, K Bruce, D Connachan, R Cook, A Daniell, A Elliott, M Fung, HKF Irving, A Laurie, S Lee, YJ Lim, ZX Maddineni, S McClenaghan, RE Muthuganesan, V Ravichandran, P Roberts, N Shaji, S Solt, S Toshney, E Arnold, C Baker, O Belais, F Bojanic, C Byrne, M Chau, CYC De Soysa, S Eldridge, M Fairey, M Fearnhead, N Guéroult, A Ho, JSY Joshi, K Kadiyala, N Khalid, S Khan, F Kumar, K Lewis, E Magee, J Manetta-Jones, D Mann, S McKeown, L Mitrofan, C Mohamed, T Monnickendam, A Ng, AYKC Ortu, A Patel, M Pope, T Pressling, S Purohit, K Saji, S Shah Foridi, J Shah, R Siddiqui, SS Surman, K Utukuri, M Varghese, A Williams, CYK Yang, JJ Billson, E Cheah, E Holmes, P Hussain, S Murdock, D Nicholls, A Patel, P Ramana, G Saleki, M Spence, H Thomas, D Yu, C Abousamra, M Brown, C Conti, I Donnelly, A Durand, M French, N Goan, R O'Kane, E Rubinchik, P Gardiner, H Kempf, B Lai, YL Matthews, H Minford, E Rafferty, C Reid, C Sheridan, N Al Bahri, T Bhoombla, N Rao, BM Titu, L Chatha, S Field, C Gandhi, T Gulati, R Jha, R Jones Sam, MT Karim, S Patel, R Saunders, M Sharma, K Abid, S Heath, E Kurup, D Patel, A Ali, M Cresswell, B Felstead, D Jennings, K Kaluarachchi, T Lazzereschi, L Mayson, H Miah, JE Reinders, B Rosser, A Thomas, C Williams, H Al-Hamid, Z Alsadoun, L Chlubek, M Fernando, P Gaunt, E Gercek, Y Maniar, R Ma, R Matson, M Moore, S Morris, A Nagappan, PG Ratnayake, M Rockall, L Shallcross, O Sinha, A Tan, KE Virdee, S Wenlock, R Donnelly, HA Ghazal, R Hughes, I Liu, X McFadden, M Misbert, E Mogey, P O'Hara, A Peace, C Rainey, C Raja, P Salem, M Salmon, J Tan, CH Alves, D Bahl, S Baker, C Coulthurst, J Koysombat, K Linn, T Rai, P Sharma, A Shergill, A Ahmed, M Ahmed, S Belk, LH Choudhry, H Cummings, D Dixon, Y Dobinson, C Edwards, J Flint, J Franco Da Silva, C Gallie, R Gardener, M Glover, T Greasley, M Hatab, A Howells, R Hussey, T Khan, A Mann, A Morrison, H Ng, A Osmond, R Padmakumar, N Pervaiz, F Prince, R Qureshi, A Sawhney, R Sigurdson, B Stephenson, L Vora, K Zacken, A Cope, P Di Traglia, R Ferarrio, I Hackett, N Healicon, R Horseman, L Lam, LI Meerdink, M Menham, D Murphy, R Nimmo, I Ramaesh, A Rees, J Soame, R Dilaver, N Adebambo, D Brown, E Burt, J Foster, K Kaliyappan, L Knight, P Politis, A Richardson, E Townsend, J Abdi, M Ball, M Easby, S Gill, N Ho, E Iqbal, H Matthews, M Nubi, S Nwokocha, JO Okafor, I Perry, G Sinartio, B Vanukuru, N Walkley, D Welch, T Yates, J Yeshitila, N Bryans, K Campbell, B Gray, C Keys, R Macartney, M Chamberlain, G Khatri, A Kucheria, A Lee, STP Reese, G Roy choudhury, J Tan, WYR Teh, JJ Ting, A Kazi, S Kontovounisios, C Vutipongsatorn, K Amarnath, T Balasubramanian, N Bassett, E Gurung, P Lim, J Panjikkaran, A Sanalla, A Alkoot, M Bacigalupo, V Eardley, N Horton, M Hurry, A Isti, C Maskell, P Nursiah, K Punn, G Salih, H Epanomeritakis, E Foulkes, A Henderson, R Johnston, E McCullough, H McLarnon, M Morrison, E Cheung, A Cho, SH Eriksson, F Hedges, J Low, Z May, C Musto, L Nagi, S Nur, S Salau, E Shabbir, S Thomas, MC Uthayanan, L Vig, S Zaheer, M Zeng, G Ashcroft-Quinn, S Brown, R Hayes, J McConville, R French, R Gilliam, A Sheetal, S Shehzad, MU Bani, W Christie, I Franklyn, J Khan, M Russell, J Smolarek, S Varadarassou, R Ahmed, SK Narayanaswamy, S Sealy, J Shah, M Dodhia, V Manukyan, A O'Hare, R Orbell, J Chung, I Forenc, K Gupta, A Agarwal, A Al Dabbagh, A Bennewith, R Bottomley, J Chu, TSM Chu, YYA Doherty, W Evans, B Hainsworth, P Hosfield, T Li, CH McCullagh, I Mehta, A Thaker, A Thompson, B Virdi, A Walker, H Wilkins, E Dixon, C Hassan, MR Lotca, N Tong, KS Batchelor-Parry, H Chaudhari, S Harris, T Hooper, J Johnson, C Mulvihill, C Nayler, J Olutobi, O Piramanayagam, B Stones, K Sussman, M Weaver, C Alam, F Al Rawi, M Andrew, F Arrayeh, A Azizan, N Hassan, A Iqbal, Z John, I Jones, M Kalake, O Keast, M Nicholas, J Patil, A Powell, K Roberts, P Sabri, A Segue, AK Shah, A Shaik Mohamed, SA Shehadeh, A Shenoy, S Tong, A Upcott, M Vijayasingam, D Anarfi, S Dauncey, J Devindaran, A Havalda, P Komninos, G Mwendwa, E Norman, C Richards, J Urquhart, A Allan, J Cahya, E Hunt, H McWhirter, C Norton, R Roxburgh, C Tan, JY Ali Butt, S Hansdot, S Haq, I Mootien, A Sanchez, I Vainas, T Deliyannis, E Tan, M Vipond, M Chittoor Satish, NN Dattani, A De Carvalho, L Gaston-Grubb, M Karunanithy, L Lowe, B Pace, C Raju, K Roope, J Taylor, C Youssef, H Munro, T Thorn, C Wong, KHF Yunus, A Chawla, S Datta, A Dinesh, AA Field, D Georgi, T Gwozdz, A Hamstead, E Howard, N Isleyen, N Jackson, N Kingdon, J Sagoo, KS Schizas, A Yin, L Aung, E Aung, YY Franklin, S Han, SM Kim, WC Martin Segura, A Rossi, M Ross, T Tirimanna, R Wang, B Zakieh, O Ben-Arzi, H Flach, A Jackson, E Magers, S Olu abara, C Rogers, E Sugden, K Tan, H Veliah, S Walton, U Asif, A Bharwada, Y Bowley, D Broekhuizen, A Cooper, L Evans, N Girdlestone, H Ling, C Mann, H Mehmood, N Mulvenna, CL Rainer, N Trout, I Gujjuri, R Jeyaraman, D Leong, E Singh, D Smith, E Anderton, J Barabas, M Goyal, S Howard, D Joshi, A Mitchell, D Weatherby, T Badminton, R Bird, R Burtle, D Choi, NY Devalia, K Farr, E Fischer, F Fish, J Gunn, F Jacobs, D Johnston, P Kalakoutas, A Lau, E Loo, YNAF Louden, H Makariou, N Mohammadi, K Nayab, Y Ruhomaun, S Ryliskyte, R Saeed, M Shinde, P Sudul, M Theodoropoulou, K Valadao-Spoorenberg, J Vlachou, F Arshad, SR Janmohamed, AM Noor, M Oyerinde, O Saha, A Syed, Y Watkinson, W Ahmadi, H Akintunde, A Alsaady, A Bradley, J Brothwood, D Burton, M Higgs, M Hoyle, C Katsura, C Lathan, R Louani, A Mandalia, R Prihartadi, AS Qaddoura, B Sandland-Taylor, L Thadani, S Thompson, A Walshaw, J Teo, S Ali, S Bawa, JH Fox, S Gargan, K Haider, SA Hanna, N Hatoum, A Khan, Z Krzak, AM Li, T Pitt, J Tan, GJS Ullah, Z Wilson, E Cleaver, J Colman, J Copeland, L Coulson, A Davis, P Faisal, H Hassan, F Hughes, JT Jabr, Y Mahmoud Ali, F Nahaboo Solim, ZN Sangheli, A Shaya, S Thompson, R Cornwall, H De Andres Crespo, M Fay, E Findlay, J Groves, E Jones, O Killen, A Millo, J Thomas, S Ward, J Wilkins, M Zaki, F Zilber, E Bhavra, K Bilolikar, A Charalambous, M Elawad, A Eleni, A Fawdon, R Gibbins, A Livingstone, D Mala, D Oke, SE Padmakumar, D Patsalides, MA Payne, D Ralphs, C Roney, A Sardar, N Stefanova, K Surti, F Timms, R Tosney, G Bannister, J Clement, NS Cullimore, V Kamal, F Lendor, J McKay, J Mcswiggan, J Minhas, N Seneviratne, K Simeen, S Valverde, J Watson, N Bloom, I Dinh, TH Hirniak, J Joseph, R Kansagra, M Lai, CKN Melamed, N Patel, J Randev, J Sedighi, T Shurovi, B Sodhi, J Vadgama, N Abdulla, S Adabavazeh, B Champion, A Chennupati, R Chu, K Devi, S Haji, A Schulz, J Testa, F Davies, P Gurung, B Howell, S Modi, P Pervaiz, A Zahid, M Abdolrazaghi, S Abi Aoun, R Anjum, Z Bawa, G Bhardwaj, R Brown, S Enver, M Gill, D Gopikrishna, D Gurung, D Kanwal, A Kaushal, P Khanna, A Lovell, E McEvoy, C Mirza, M Nabeel, S Naseem, S Pandya, K Perkins, R Pulakal, R Ray, M Reay, C Reilly, S Round, A Seehra, J Shakeel, NM Singh, B Vijay Sukhnani, M Brown, L Desai, B Elzanati, H Godhaniya, J Kavanagh, E Kent, J Kishor, A Liu, A Norwood, M Shaari, N Wood, C Wood, M Brown, A Chellapuri, A Ferriman, A Ghosh, I Kulkarni, N Noton, T Pinto, A Rajesh, S Varghese, B Wenban, C Aly, R Barciela, C Brookes, T Corrin, E Goldsworthy, M Mohamed Azhar, MS Moore, J Nakhuda, S Ng, D Pillay, S Port, S Abdullah, M Akinyemi, J Islam, S Kale, A Lewis, A Manjunath, T McCabe, H Misra, S Stubley, T Tam, JP Waraich, N Chaora, T Ford, C Osinkolu, I Pong, G Rai, J Risquet, R Ainsworth, J Ayandokun, P Barham, E Barrett, G Barry, J Bisson, E Bridges, I Burke, D Cann, J Cloney, M Coates, S Cripps, P Davies, C Francis, N Green, S Handley, G Hathaway, D Hurt, L Jenkins, S Johnston, C Khadka, A McGee, U Morris, D Murray, R Norbury, C Pierrepont, Z Richards, C Ross, O Ruddy, A Salmon, C Shield, M Soanes, K Spencer, N Taverner, S Williams, C Wills-Wood, W Woodward, S Chow, J Fan, J Guest, O Hunter, I Moon, WY Arthur-Quarm, S Edwards, P Hamlyn, V McEneaney, L N D, G Pranoy, S Ting, M Abada, S Alawattegama, LH Ashok, A Carey, C Gogna, A Haglund, C Hurley, P Leelo, N Liu, B Mannan, F Paramjothy, K Ramlogan, K Raymond-Hayling, O Shanmugarajah, A Solichan, D Wilkinson, B Ahmad, NA Allan, D Amin, A Bakina, C Burns, F Cameron, F Campbell, A Cavanagh, S Chan, SMZ Chapman, S Chong, V Edelsten, E Ekpete, O El Sheikh, M Ghose, R Hassane, A Henderson, C Hilton-Christie, S Husain, M Hussain, H Javid, Z Johnson-Ogbuneke, J Johnston, A Khalil, M Leung, TCC Makin, I Muralidharan, V Naeem, M Patil, P Ravichandran, S Saraeva, D Shankey-Smith, W Sharma, N Swan, R Waudby-West, R Wilkinson, A Wright, K Balasubramanian, A Bhatti, S Chalkley, M Chou, WK Dixon, M Evans, L Fisher, K Gandhi, P Ho, S Lau, YB Lowe, S Meechan, C Murali, N Musonda, C Njoku, P Ochieng, L Pervez, MU Seebah, K Shaikh, I Sikder, MA Vanker, R Alom, J Bajaj, V Coleman, O Finch, G Goss, J Jenkins, C Kontothanassis, A Liew, MS Ng, K Outram, M Shakeel, MM Tawn, J Zuhairy, S Chapple, K Cinnamond, A Coleman, S George, HA Goulder, L Hare, N Hawksley, J Kret, A Luesley, A Mecia, L Porter, H Puddy, E Richardson, G Sohail, B Srikaran, V Tadross, D Tobin, J Tokidis, E Young, L Ashdown, T Bratsos, S Koomson, A Kufuor, A Lim, MQ Shah, S Thorne, EPC Warusavitarne, J Xu, S Abigail, S Ahmed, A Ahmed, J Akmal, A Al-Khafaji, M Amini, B Arshad, M Bogie, E Brazkiewicz, M Carroll, M Chandegra, A Cirelli, C Deng, A Fairclough, S Fung, YJ Gornell, C Green, RL Green, SV Gulamhussein, AHM Isaac, AG Jan, R Jegatheeswaran, L Knee, M Kotecha, J Kotecha, S Maxwell-Armstrong, C McIntyre, C Mendis, N Naing, TKP Oberman, J Ong, ZX Ramalingam, A Saeed Adam, A Tan, LL Towell, S Yadav, J Anandampillai, R Chung, S Hounat, A Ibrahim, B Jeyakumar, G Khalil, A Khan, UA Nair, G Owusu-Ayim, M Wilson, M Kanani, A Kilkelly, B Ogunmwonyi, I Ong, L Samra, B Schomerus, L Shea, J Turner, O Yang, Y Amin, M Blott, N Clark, A Feather, A Forrest, M Hague, S Hamilton, K Higginbotham, G Hope, E Karimian, S Loveday, K Malik, H McKenna, O Noor, A Onsiong, C Patel, B Radcliffe, N Shah, P Tye, L Verma, K Walford, R Yusufi, U Zachariah, M Casey, A Doré, C Fludder, V Fortescue, L Kalapu, SS Karel, E Khera, G Smith, C Appleton, B Ashaye, A Boggon, E Evans, A Faris Mahmood, H Hinchcliffe, Z Marei, O Silva, I Spooner, C Thomas, G Timlin, M Wellington, J Yao, SL Abdelrazek, M Abdelrazik, Y Bee, F Joseph, A Mounce, A Parry, G Vignarajah, N Biddles, D Creissen, A Kolhe, S K, T Lea, A Ledda, V O'Loughlin, P Scanlon, J Shetty, N Weller, C Abdalla, M Adeoye, A Bhatti, M Chadda, KR Chu, J Elhakim, H Foster-Davies, H Rabie, M Tailor, B Webb, S Abdelrahim, ASA Choo, SY Jiwa, A Mangam, S Murray, S Shandramohan, A Aghanenu, O Budd, W Hayre, J Khanom, S Liew, ZY McKinney, R Moody, N Muhammad-Kamal, H Odogwu, J Patel, D Roy, C Sattar, Z Shahrokhi, N Sinha, I Thomson, E Wonga, L Bain, J Khan, J Ricardo, D Bevis, R Cherry, C Darkwa, S Drew, W Griffiths, E Konda, N Madani, D Mak, JKC Meda, B Odunukwe, U Preest, G Raheel, F Rajaseharan, A Ramgopal, A Risbrooke, C Selvaratnam, K Sethunath, G Tabassum, R Taylor, J Thakker, A Wijesingha, N Wybrew, R Yasin, T Ahmed Osman, A Alfadhel, S Carberry, E Chen, JY Drake, I Glen, P Jayasuriya, N Kawar, L Myatt, R Sinan, LOH Siu, SSY Tjen, V Adeboyejo, O Bacon, H Barnes, R Birnie, C D'Cunha Kamath, A Hughes, E Middleton, S Owen, R Schofield, E Short, C Smith, R Wang, H Willett, M Zimmerman, M Balfour, J Chadwick, T Coombe-Jones, M Do Le, HP Faulkner, G Hobson, K Shehata, Z Beattie, M Chmielewski, G Chong, C Donnelly, B Drusch, B Ellis, J Farrelly, C Feyi-Waboso, J Hibell, I Hoade, L Ho, C Jones, H Kodiatt, B Lidder, P Ni Cheallaigh, L Norman, R Patabendi, I Penfold, H Playfair, M Pomeroy, S Ralph, C Rottenburg, H Sebastian, J Sheehan, M Stanley, V Welchman, J Ajdarpasic, D Antypas, A Azouaghe, O Basi, S Bettoli, G Bhattarai, S Bommireddy, L Bourne, K Budding, J Cookey-Bresi, R Cummins, T Davies, G Fabelurin, C Gwilliam, R Hanley, J Hird, A Kruczynska, A Langhorne, B Lund, J Lutchman, I McGuinness, R Neary, M Pampapathi, S Pang, E Podbicanin, S Rai, N Redhouse White, G Sujith, J Thomas, P Walker, I Winterton, R Anderson, P Barrington, M Bhadra, K Clark, G Fowler, G Gibson, C Hudson, S Kaminskaite, V Lawday, S Longshaw, A MacKrill, E McLachlan, F Murdeshwar, A Nieuwoudt, R Parker, P Randall, R Rawlins, E Reeves, SA Rye, D Sirkis, T Sykes, B Ventress, N Wosinska, N Akram, B Burton, L Coombs, A Long, R Magowan, D Ong, C Sethi, M Williams, G Chan, C Chan, LH Fernando, D Gaba, F Khor, Z Les, JW Mak, R Moin, S Ng Kee Kwong, KC Paterson-Brown, S Tew, YY Bardon, A Burrell, K Coldwell, C Costa, I Dexter, E Hardy, A Khojani, M Mazurek, J Raymond, T Reddy, V Reynolds, J Soma, A Agiotakis, S Alsusa, H Desai, N Peristerakis, I Adcock, A Ayub, H Bennett, T Bibi, F Brenac, S Chapman, T Clarke, G Clark, F Galvin, C Gwyn-Jones, A Henry-Blake, C Kerner, S Kiandee, M Lovett, A Pilecka, A Ravindran, R Siddique, H Sikand, T Treadwell, K Akmal, K Apata, A Barton, O Broad, G Darling, H Dhuga, Y Emms, L Habib, S Jain, R Jeater, J Kan, CYP Kathiravelupillai, A Khatkar, H Kirmani, S Kulasabanathan, K Lacey, H Lal, K Manafa, C Mansoor, M McDonald, S Mittal, A Mustoe, S Nottrodt, L Oliver, P Papapetrou, I Pattinson, F Raja, M Reyhani, H Shahmiri, A Small, O Soni, U Aguirrezabala Armbruster, B Bunni, J Hakim, MA Hawkins-Hooker, L Howell, KA Hullait, R Jaskowska, A Ottewell, L Thomas-Jones, I Vasudev, A Clements, B Fenton, J Gill, M Haider, S Lim, AJM Maguire, H McMullan, J Nicoletti, J Samuel, S Unais, MA White, N Yao, PC Yow, L Boyle, C Brady, R Cheekoty, P Cheong, J Chew, SJHL Chow, R Ganewatta Kankanamge, D Mamer, L Mohammed, B Ng Chieng Hin, J Renji Chungath, R Royston, A Sharrad, E Sinclair, R Tingle, S Treherne, K Wyatt, F Maniarasu, VS Moug, S Appanna, T Bucknall, T Hussain, F Owen, A Parry, M Parry, R Sagua, N Spofforth, K Yuen, ECT Bosley, N Hardie, W Moore, T Regas, C Abdel-Khaleq, S Ali, N Bashiti, H Buxton-Hopley, 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| Item Type: | Journal Article |
| Abstract: | Background Stratifying risk of postoperative pulmonary complications after major abdominal surgery allows clinicians to modify risk through targeted interventions and enhanced monitoring. In this study, we aimed to identify and validate prognostic models against a new consensus definition of postoperative pulmonary complications. Methods We did a systematic review and international external validation cohort study. The systematic review was done in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We searched MEDLINE and Embase on March 1, 2020, for articles published in English that reported on risk prediction models for postoperative pulmonary complications following abdominal surgery. External validation of existing models was done within a prospective international cohort study of adult patients (≥18 years) undergoing major abdominal surgery. Data were collected between Jan 1, 2019, and April 30, 2019, in the UK, Ireland, and Australia. Discriminative ability and prognostic accuracy summary statistics were compared between models for the 30-day postoperative pulmonary complication rate as defined by the Standardised Endpoints in Perioperative Medicine Core Outcome Measures in Perioperative and Anaesthetic Care (StEP-COMPAC). Model performance was compared using the area under the receiver operating characteristic curve (AUROCC). Findings In total, we identified 2903 records from our literature search; of which, 2514 (86·6%) unique records were screened, 121 (4·8%) of 2514 full texts were assessed for eligibility, and 29 unique prognostic models were identified. Nine (31·0%) of 29 models had score development reported only, 19 (65·5%) had undergone internal validation, and only four (13·8%) had been externally validated. Data to validate six eligible models were collected in the international external validation cohort study. Data from 11 591 patients were available, with an overall postoperative pulmonary complication rate of 7·8% (n=903). None of the six models showed good discrimination (defined as AUROCC ≥0·70) for identifying postoperative pulmonary complications, with the Assess Respiratory Risk in Surgical Patients in Catalonia score showing the best discrimination (AUROCC 0·700 [95% CI 0·683–0·717]). Interpretation In the pre-COVID-19 pandemic data, variability in the risk of pulmonary complications (StEP-COMPAC definition) following major abdominal surgery was poorly described by existing prognostication tools. To improve surgical safety during the COVID-19 pandemic recovery and beyond, novel risk stratification tools are required. Funding British Journal of Surgery Society. |
| Issue Date: | Jul-2022 |
| Date of Acceptance: | 1-Jun-2022 |
| URI: | http://hdl.handle.net/10044/1/98249 |
| DOI: | 10.1016/s2589-7500(22)00069-3 |
| ISSN: | 2589-7500 |
| Publisher: | Elsevier BV |
| Start Page: | e520 |
| End Page: | e531 |
| Journal / Book Title: | The Lancet Digital Health |
| Volume: | 4 |
| Issue: | 7 |
| Copyright Statement: | © 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license. |
| Publication Status: | Published |
| Online Publication Date: | 2022-06-21 |
| Appears in Collections: | Department of Surgery and Cancer |
This item is licensed under a Creative Commons License
