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A case of active Covid-19 infection and transmission after the first dose of the BNT162b2 mRNA vaccination in Saudi Arabia: A case report

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Title: A case of active Covid-19 infection and transmission after the first dose of the BNT162b2 mRNA vaccination in Saudi Arabia: A case report
Authors: Allam, AA
Sayed, AA
Item Type: Journal Article
Abstract: A 47-year-old non-smoker male who has received the first dose of the BNT162b2 mRNA Covid-19 vaccine in Saudi Arabia. At day 3 post-vaccination, he tested negative for Covid-19 and travelled to Egypt. On day 12 he developed runny nose, body ache and fever, and he reportedly tested (PCR) negative for Covid-19 Upon his return to Saudi on day 15, his symptoms have worsened and he presented to the Emergency Department, at which he tested positive for Covid-19. The patient was overweight (BMI = 29), was not suffering from any comorbidities and was not taking any medication. Upon examination, he was vitally stable and his laboratory investigation only revealed a slightly increased Creatinine. His chest X-ray was unremarkable. His condition did not require hospital admission, so he was discharged and advised to home-isolate himself. Four days after his discharge, his entire household came to the hospital and tested positive for Covid-19. This is the first case report, in Saudi Arabia, of a person receiving the first dose of the BNT162b2 vaccine and got infected with Covid-19 afterwards. The report highlights the significance of receiving the second dose of the vaccine to be effective. It also demonstrates that those with a single dose mRNA vaccine, could get infected and transmit the infection.
Issue Date: Aug-2021
Date of Acceptance: 7-Jul-2021
URI: http://hdl.handle.net/10044/1/90497
DOI: 10.1016/j.jiph.2021.07.006
ISSN: 1876-0341
Publisher: Elsevier BV
Start Page: 1123
End Page: 1125
Journal / Book Title: Journal of Infection and Public Health
Volume: 14
Issue: 8
Copyright Statement: © 2021 Published by Elsevier Ltd on behalf of King Saud Bin Abdulaziz University for Health Sciences. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Keywords: 1117 Public Health and Health Services
1199 Other Medical and Health Sciences
Publication Status: Published
Open Access location: https://www.sciencedirect.com/science/article/pii/S1876034121001933/pdfft?md5=610398d503fb1e50d5504dca4ccb229f&pid=1-s2.0-S1876034121001933-main.pdf
Online Publication Date: 2021-07-13
Appears in Collections:Department of Surgery and Cancer
Department of Infectious Diseases
Imperial College London COVID-19



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