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Unmet medical needs in metastatic lung and digestive neuroendocrine neoplasms
| File | Description | Size | Format | |
|---|---|---|---|---|
 Umet needs in G3- enets-v 311017.docx | Accepted version | 316.44 kB | Microsoft Word | View/Open |
| Title: | Unmet medical needs in metastatic lung and digestive neuroendocrine neoplasms |
| Authors: | Capdevila, J Bodei, L Davies, P Gorbounova, V Jensen, RT Knigge, UP Krejs, GJ Krenning, E O'Connor, JM Peeters, M Rindi, G Salazar, R Vullierme, M-P Pavel, ME Arnold, R Bartsch, D Baudin, E Bodei, L Borbath, I Capdevila, J Caplin, M Chen, J Costa, F Couvelard, A Cwikla, JB Davies, P De Herder, WW Falconi, M Falkerby, J Fazio, N Ferone, D Frilling, A Garcia-Carbonero, R Glasberg, S Gorbunova, V Grossman, A Hoersch, D Jensen, RT Kaltsas, G Kloeppel, G Knigge, UP Kos-Kudla, B Krejs, GJ Krenning, E Kulke, M Lamberts, SWJ Van Dijkum, NE O'Connor, JM O'Toole, D Pape, UF Partelli, S Pavel, ME Peeters, M Ramage, J Reed, NSB Rindi, G Rinke, A Ruszniewski, P Sorbye, H Sundin, A Scoazec, JY Taal, BG Tiensuu, JE Toumpanakis, C Valle, J Vullierme, MP Welin, S Wiedenmann, B |
| Item Type: | Journal Article |
| Abstract: | Unmet medical needs are not infrequent in oncology, and these needs are usually of higher magnitude in rare cancers. The field of neuroendocrine neoplasms (NENs) has evolved rapidly during the last decade, and, currently, a new WHO classification is being implemented and several treatment options are available in the metastatic setting after the results of prospective phase III clinical trials. However, several questions are still unanswered, and decisions in our daily clinical practice should be made with limited evidence. In the 2016 meeting of the advisory board of the European Neuroendocrine Tumor Society (ENETS), the main unmet medical needs in the metastatic NENs setting were deeply discussed, and several proposals to try to solve them are presented in this article, including biomarkers, imaging, and therapy. |
| Issue Date: | 1-Jan-2019 |
| Date of Acceptance: | 27-Aug-2018 |
| URI: | http://hdl.handle.net/10044/1/67386 |
| DOI: | https://dx.doi.org/10.1159/000493319 |
| ISSN: | 0028-3835 |
| Publisher: | Karger Publishers |
| Start Page: | 18 |
| End Page: | 25 |
| Journal / Book Title: | Neuroendocrinology |
| Volume: | 108 |
| Issue: | 1 |
| Copyright Statement: | © 2018 S. Karger AG, Basel. |
| Sponsor/Funder: | Dr. Heinz-Horst Deichmann Stiftung |
| Funder's Grant Number: | n/a |
| Keywords: | Science & Technology Life Sciences & Biomedicine Endocrinology & Metabolism Neurosciences Neurosciences & Neurology Unmet medical needs Neuroendocrine neoplasms Metastasis Biomarkers Imaging Therapy TUMORS SUNITINIB LANREOTIDE EVEROLIMUS SURVIVAL ENETS 2016 Munich Advisory Board Participants ENETS 2016 Munich Advisory Board Participants 1103 Clinical Sciences 1109 Neurosciences |
| Publication Status: | Published |
| Online Publication Date: | 2018-08-28 |
| Appears in Collections: | Department of Surgery and Cancer |