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Diverse modes of binding in structures of Leishmania major N-myristoyltransferase with selective inhibitors

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Title: Diverse modes of binding in structures of Leishmania major N-myristoyltransferase with selective inhibitors
Authors: Brannigan, JA
Roberts, SM
Bell, AS
Hutton, JA
Hodgkinson, MR
Tate, EW
Leatherbarrow, RJ
Smith, DF
Wilkinson, AJ
Item Type: Journal Article
Issue Date: 1-Jul-2014
URI: http://hdl.handle.net/10044/1/26922
DOI: https://dx.doi.org/10.1107/S2052252514013001
ISSN: 2052-2525
Publisher: International Union of Crystallography: IUCrJ
Start Page: 250
End Page: 260
Journal / Book Title: IUCrJ
Volume: 1
Copyright Statement: © 2014 The Authors. Creative Commons Attribution License
Keywords: Science & Technology
Physical Sciences
Technology
Chemistry, Multidisciplinary
Crystallography
Materials Science, Multidisciplinary
Chemistry
Materials Science
N-myristoyltransferase
inhibitor
ligand binding
Leishmania
drug discovery
CEREVISIAE MYRISTOYL-COA
POTENTIAL-DRUG TARGET
PLASMODIUM-FALCIPARUM
CANDIDA-ALBICANS
CRYPTOCOCCUS-NEOFORMANS
BOUND MYRISTOYLCOA
CRYSTAL-STRUCTURES
DISCOVERY
DESIGN
TRANSFERASE
Publication Status: Published
Appears in Collections:Chemistry
Biological and Biophysical Chemistry
Faculty of Natural Sciences