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Design and Synthesis of Inhibitors of Plasmodium falciparum N-Myristoyltransferase, A Promising Target for Antimalarial Drug Discovery

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Title: Design and Synthesis of Inhibitors of Plasmodium falciparum N-Myristoyltransferase, A Promising Target for Antimalarial Drug Discovery
Authors: Yu, Z
Brannigan, JA
Moss, DK
Brzozowski, AM
Wilkinson, AJ
Holder, AA
Tate, EW
Leatherbarrow, RJ
Item Type: Journal Article
Issue Date: 25-Oct-2012
Date of Acceptance: 3-Oct-2012
URI: http://hdl.handle.net/10044/1/26844
DOI: https://dx.doi.org/10.1021/jm301160h
ISSN: 0022-2623
Publisher: American Chemical Society
Start Page: 8879
End Page: 8890
Journal / Book Title: Journal of Medicinal Chemistry
Volume: 55
Issue: 20
Copyright Statement: This document is the Accepted Manuscript version of a Published Work that appeared in final form in Journal of Medicinal Chemistry, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://dx.doi.org/10.1021/jm301160h
Keywords: Science & Technology
Life Sciences & Biomedicine
Chemistry, Medicinal
Pharmacology & Pharmacy
CHEMISTRY, MEDICINAL
ADP-RIBOSYLATION FACTOR
MYRISTOYL-COA
SELECTIVE INHIBITORS
CANDIDA-ALBICANS
ESSENTIAL ENZYME
STARTING POINTS
MALARIA
IDENTIFICATION
BENZOFURANS
MECHANISM
Publication Status: Published
Appears in Collections:Chemistry
Biological and Biophysical Chemistry
Faculty of Natural Sciences