Diabetes mellitus and latent tuberculosis infection: baseline analysis of a large UK cohort
File(s)
Accepted version
Accepted version
Author(s)
Type
Journal Article
Abstract
We conducted a cross-sectional analysis of baseline data from a UK cohort study which enrolled participants at risk of latent tuberculosis infection (LTBI, defined as a positive result for either of the two interferon gamma release assays). Binomial regression with a log link was used to estimate crude and adjusted prevalence ratios (PRs) and 95% CIs for the relationship between diabetes mellitus (DM) and LTBI. Adjusted for age, sex, ethnicity, body mass index and the presence of other immunocompromising conditions, DM was associated with a 15% higher prevalence of LTBI (adjusted PR=1.15, 95% CI 1.02 to 1.30, p=0.025).
Date Issued
2018-12-13
Date Acceptance
2018-04-09
Citation
Thorax, 2018, 74, pp.91-94
ISSN
1468-3296
Publisher
BMJ Publishing Group
Start Page
91
End Page
94
Journal / Book Title
Thorax
Volume
74
Copyright Statement
© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
Sponsor
National Institute for Health Research
National Institute for Health Research
Grant Number
NF-SI-0508-10179
NF-SI-0513-10155
Subjects
Science & Technology
Life Sciences & Biomedicine
Respiratory System
RISK
clinical epidemiology
tuberculosis
Adolescent
Adult
Cross-Sectional Studies
Diabetes Mellitus
Female
Humans
Interferon-gamma Release Tests
Latent Tuberculosis
Male
Middle Aged
Prevalence
United Kingdom
Young Adult
Humans
Diabetes Mellitus
Prevalence
Cross-Sectional Studies
Adolescent
Adult
Middle Aged
Female
Male
Young Adult
Latent Tuberculosis
Interferon-gamma Release Tests
United Kingdom
Respiratory System
1103 Clinical Sciences
Publication Status
Published
Date Publish Online
2018-05-15