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2020 FDA TIDES (peptides and oligonucleotides) harvest
| File | Description | Size | Format | |
|---|---|---|---|---|
 2020 FDA TIDES (Peptides and Oligonucleotides) Harvest.pdf | Published version | 1.73 MB | Adobe PDF | View/Open |
| Title: | 2020 FDA TIDES (peptides and oligonucleotides) harvest |
| Authors: | Al Musaimi, O Al Shaer, D Albericio, F De la Torre, BG |
| Item Type: | Journal Article |
| Abstract: | 2020 has been an extremely difficult and challenging year as a result of the coronavirus disease 2019 (COVID-19) pandemic and one in which most efforts have been channeled into tackling the global health crisis. The US Food and Drug Administration (FDA) has approved 53 new drug entities, six of which fall in the peptides and oligonucleotides (TIDES) category. The number of authorizations for these kinds of drugs has been similar to that of previous years, thereby reflecting the consolidation of the TIDES market. Here, the TIDES approved in 2020 are analyzed in terms of chemical structure, medical target, mode of action, and adverse effects. |
| Issue Date: | 11-Feb-2021 |
| Date of Acceptance: | 9-Feb-2021 |
| URI: | http://hdl.handle.net/10044/1/94838 |
| DOI: | 10.3390/ph14020145 |
| ISSN: | 1424-8247 |
| Publisher: | MDPI AG |
| Journal / Book Title: | Pharmaceuticals |
| Volume: | 14 |
| Issue: | 2 |
| Copyright Statement: | © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/) |
| Keywords: | Science & Technology Life Sciences & Biomedicine Chemistry, Medicinal Pharmacology & Pharmacy belantamab mafodotin-blmf Cu-64-DOTATATE drugs FDA Ga-68-PSMA-11 lumasiran setmelanotide oligonucleotides peptides viltolarsen 64Cu-DOTATATE 68Ga-PSMA-11 FDA belantamab mafodotin-blmf drugs lumasiran oligonucleotides peptides setmelanotide viltolarsen Science & Technology Life Sciences & Biomedicine Chemistry, Medicinal Pharmacology & Pharmacy belantamab mafodotin-blmf Cu-64-DOTATATE drugs FDA Ga-68-PSMA-11 lumasiran setmelanotide oligonucleotides peptides viltolarsen 1115 Pharmacology and Pharmaceutical Sciences |
| Publication Status: | Published |
| Open Access location: | https://www.mdpi.com/1424-8247/14/2/145 |
| Article Number: | ARTN 145 |
| Appears in Collections: | Chemical Engineering |
This item is licensed under a Creative Commons License
