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Bone Marrow Transplantation 1957-2019
| File | Description | Size | Format | |
|---|---|---|---|---|
 Bone Marrow Transplantation 1957-2019.pdf | Published version | 430.65 kB | Adobe PDF | View/Open |
| Title: | Bone Marrow Transplantation 1957-2019 |
| Authors: | Simpson, E Dazzi, F |
| Item Type: | Journal Article |
| Abstract: | Clinical bone marrow transplantation started in 1957 at a time when remarkably little was known about hematopoietic stems cells, immune responses to transplants or the identity of transplant antigens. This review will delineate the substantial increase in knowledge about these three areas gained between then and 1992 when the Ceppellini School course on Bone Marrow Transplantation was held, along with the progress made in clinical application, as well as the stumbling blocks that remained to be overcome by further research to advance knowledge. It will outline the significant progress made between 1992 and the present year, 2019, and the remaining problems. |
| Issue Date: | 5-Jun-2019 |
| Date of Acceptance: | 16-May-2019 |
| URI: | http://hdl.handle.net/10044/1/71887 |
| DOI: | https://doi.org/10.3389/fimmu.2019.01246 |
| ISSN: | 1664-3224 |
| Publisher: | Frontiers Media |
| Journal / Book Title: | Frontiers in Immunology |
| Volume: | 10 |
| Copyright Statement: | © 2019 Simpson and Dazzi. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
| Sponsor/Funder: | Leukaemia & Lymphoma Research "Beating Blood Cancers" Leukaemia & Lymphoma Research "Beating Blood Cancers" Cancer Research UK Leukaemia & Lymphoma Research "Beating Blood Cancers" Medical Research Council (MRC) Leukaemia & Lymphoma Research "Beating Blood Cancers" |
| Funder's Grant Number: | 0143 0325 C10437/A4395 0394 G9900299 Grant ID 48490 9952 |
| Keywords: | Science & Technology Life Sciences & Biomedicine Immunology transplantation histocompatibility graft-vs.-host graft-vs.-tumour immunosuppression HEMATOPOIETIC STEM-CELLS Y-ANTIGEN T-CELLS INFUSION graft-vs.-host graft-vs.-tumour histocompatibility immunosuppression transplantation Science & Technology Life Sciences & Biomedicine Immunology transplantation histocompatibility graft-vs.-host graft-vs.-tumour immunosuppression HEMATOPOIETIC STEM-CELLS Y-ANTIGEN T-CELLS INFUSION |
| Publication Status: | Published online |
| Article Number: | 1246 |
| Online Publication Date: | 2019-06-05 |
| Appears in Collections: | Department of Medicine (up to 2019) |