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Demonstration of the Blood-Stage Plasmodium falciparum Controlled Human Malaria Infection Model to Assess Efficacy of the P. falciparum Apical Membrane Antigen 1 Vaccine, FMP2.1/AS01

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Title: Demonstration of the Blood-Stage Plasmodium falciparum Controlled Human Malaria Infection Model to Assess Efficacy of the P. falciparum Apical Membrane Antigen 1 Vaccine, FMP2.1/AS01
Authors: Payne, RO
Milne, KH
Elias, SC
Edwards, NJ
Douglas, AD
Brown, RE
Silk, SE
Biswas, S
Miura, K
Roberts, R
Rampling, TW
Venkatraman, N
Hodgson, SH
Labbe, GM
Halstead, FD
Poulton, ID
Nugent, FL
De Graaf, H
Sukhtankar, P
Williams, NC
Ockenhouse, CF
Kathcart, AK
Qabar, AN
Waters, NC
Soisson, LA
Birkett, AJ
Cooke, GS
Faust, SN
Woods, C
Ivinson, K
McCarthy, JS
Diggs, CL
Vekemans, J
Long, CA
Hill, AVS
Lawrie, AM
Dutta, S
Draper, SJ
Item Type: Journal Article
Issue Date: 4-Feb-2016
Date of Acceptance: 21-Jan-2016
URI: http://hdl.handle.net/10044/1/38597
DOI: http://dx.doi.org/10.1093/infdis/jiw039
ISSN: 1537-6613
Publisher: Oxford University Press
Start Page: 1743
End Page: 1751
Journal / Book Title: Journal of Infectious Diseases
Volume: 213
Issue: 11
Copyright Statement: © The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
Sponsor/Funder: Imperial College Healthcare NHS Trust
Funder's Grant Number: FR827 79560
Keywords: Science & Technology
Life Sciences & Biomedicine
Immunology
Infectious Diseases
Microbiology
malaria
AMA1
vaccine
blood stage
CHMI
PARASITE MULTIPLICATION RATES
RANDOMIZED CONTROLLED-TRIAL
CLINICAL-TRIAL
IMMUNOGENICITY
ANTIBODY
SAFETY
SPOROZOITES
VOLUNTEERS
CHALLENGE
PROTEIN
11 Medical And Health Sciences
06 Biological Sciences
Publication Status: Published
Appears in Collections:Department of Medicine (up to 2019)