Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome

Title:	Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome
Authors:	Machiela, MJ Zhou, W Karlins, E Sampson, JN Freedman, ND Yang, Q Hicks, B Dagnall, C Hautman, C Jacobs, KB Abnet, CC Aldrich, MC Amos, C Amundadottir, LT Arslan, AA Beane-Freeman, LE Berndt, SI Black, A Blot, WJ Bock, CH Bracci, PM Brinton, LA Bueno-de-Mesquita, HB Burdett, L Buring, JE Butler, MA Canzian, F Carreon, T Chaffee, KG Chang, I-S Chatterjee, N Chen, C Chen, C Chen, K Chung, CC Cook, LS Bou, MC Cullen, M Davis, FG De Vivo, I Ding, T Doherty, J Duell, EJ Epstein, CG Fan, J-H Figueroa, JD Fraumeni, JF Friedenreich, CM Fuchs, CS Gallinger, S Gao, Y-T Gapstur, SM Garcia-Closas, M Gaudet, MM Gaziano, JM Giles, GG Gillanders, EM Giovannucci, EL Goldin, L Goldstein, AM Haiman, CA Hallmans, G Hankinson, SE Harris, CC Henriksson, R Holly, EA Hong, Y-C Hoover, RN Hsiung, CA Hu, N Hu, W Hunter, DJ Hutchinson, A Jenab, M Johansen, C Khaw, K-T Kim, HN Kim, YH Kim, YT Klein, AP Klein, R Koh, W-P Kolonel, LN Kooperberg, C Kraft, P Krogh, V Kurtz, RC LaCroix, A Lan, Q Landi, MT Le Marchand, L Li, D Liang, X Liao, LM Lin, D Liu, J Lissowska, J Lu, L Magliocco, AM Malats, N Matsuo, K McNeill, LH McWilliams, RR Melin, BS Mirabello, L Moore, L Olson, SH Orlow, I Park, JY Patino-Garcia, A Peplonska, B Peters, U Petersen, GM Pooler, L Prescott, J Prokunina-Olsson, L Purdue, MP Qiao, Y-L Rajaraman, P Real, FX Riboli, E Risch, HA Rodriguez-Santiago, B Ruder, AM Savage, SA Schumacher, F Schwartz, AG Schwartz, KL Seow, A Setiawan, VW Severi, G Shen, H Sheng, X Shin, M-H Shu, X-O Silverman, DT Spitz, MR Stevens, VL Stolzenberg-Solomon, R Stram, D Tang, Z-Z Taylor, PR Teras, LR Tobias, GS Van den Berg, D Visvanathan, K Wacholder, S Wang, J-C Wang, Z Wentzensen, N Wheeler, W White, E Wiencke, JK Wolpin, BM Wong, MP Wu, C Wu, T Wu, X Wu, Y-L Wunder, JS Xia, L Yang, HP Yang, P-C Yu, K Zanetti, KA Zeleniuch-Jacquotte, A Zheng, W Zhou, B Ziegler, RG Perez-Jurado, LA Caporaso, NE Rothman, N Tucker, M Dean, MC Yeager, M Chanock, SJ
Item Type:	Journal Article
Issue Date:	13-Jun-2016
Date of Acceptance:	6-May-2016
URI:	http://hdl.handle.net/10044/1/37529
DOI:	https://dx.doi.org/10.1038/ncomms118431
ISSN:	2041-1723
Publisher:	Nature Publishing Group: Nature Communications
Journal / Book Title:	Nature Communications
Volume:	7
Copyright Statement:	This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
Keywords:	Science & Technology Multidisciplinary Sciences Science & Technology - Other Topics DETECTABLE CLONAL MOSAICISM SOMATIC MOSAICISM HUMAN GENOME CANCER BLOOD METHYLATION CELLS HEMATOPOIESIS ANEUPLOIDIES MUTATION MD Multidisciplinary
Publication Status:	Published
Article Number:	118431
Appears in Collections:	School of Public Health