Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

Title:	Factors influencing success of clinical genome sequencing across a broad spectrum of disorders
Authors:	Taylor, JC Martin, HC Lise, S Broxholme, J Cazier, J-B Rimmer, A Kanapin, A Lunter, G Fiddy, S Allan, C Aricescu, AR Attar, M Babbs, C Becq, J Beeson, D Bento, C Bignell, P Blair, E Buckle, VJ Bull, K Cais, O Cario, H Chapel, H Copley, RR Cornall, R Craft, J Dahan, K Davenport, EE Dendrou, C Devuyst, O Fenwick, AL Flint, J Fugger, L Gilbert, RD Goriely, A Green, A Greger, IH Grocock, R Gruszczyk, AV Hastings, R Hatton, E Higgs, D Hill, A Holmes, C Howard, M Hughes, L Humburg, P Johnson, D Karpe, F Kingsbury, Z Kini, U Knight, JC Krohn, J Lamble, S Langman, C Lonie, L Luck, J McCarthy, D McGowan, SJ McMullin, MF Miller, KA Murray, L Nemeth, AH Nesbit, MA Nutt, D Ormondroyd, E Oturai, AB Pagnamenta, A Patel, SY Percy, M Petousi, N Piazza, P Piret, SE Polanco-Echeverry, G Popitsch, N Powrie, F Pugh, C Quek, L Robbins, PA Robson, K Russo, A Sahgal, N Van Schouwenburg, PA Schuh, A Silverman, E Simmons, A Sorensen, PS Sweeney, E Taylor, J Thakker, RV Tomlinson, I Trebes, A Twigg, SRF Uhlig, HH Vyas, P Vyse, T Wall, SA Watkins, H Whyte, MP Witty, L Wright, B Yau, C Buck, D Humphray, S Ratcliffe, PJ Bell, JI Wilkie, AOM Bentley, D Donnelly, P McVean, G
Item Type:	Journal Article
Issue Date:	18-May-2015
Date of Acceptance:	22-Apr-2015
URI:	http://hdl.handle.net/10044/1/32124
DOI:	http://dx.doi.org/10.1038/ng.3304
ISSN:	1546-1718
Publisher:	Nature Publishing Group
Start Page:	717
End Page:	726
Journal / Book Title:	Nature Genetics
Volume:	47
Issue:	7
Copyright Statement:	© 2015 The Author(s)
Keywords:	Science & Technology Life Sciences & Biomedicine Genetics & Heredity LONG-QT SYNDROME JUVENILE MYELOMONOCYTIC LEUKEMIA SEVERE INTELLECTUAL DISABILITY DISEASE GENE-DISCOVERY OVARIAN-CANCER GERMLINE MUTATIONS BREAST-CANCER HEREDITARY BREAST CANDIDATE GENES EXOME Base Sequence DNA Mutational Analysis Genetic Diseases, Inborn Genome, Human High-Throughput Nucleotide Sequencing Humans Molecular Diagnostic Techniques Molecular Sequence Annotation Polymorphism, Single Nucleotide Sensitivity and Specificity Developmental Biology 11 Medical And Health Sciences 06 Biological Sciences
Publication Status:	Published
Appears in Collections:	Department of Medicine (up to 2019)