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Correlative light-electron microscopy shows RGD-targeted ZnO nanoparticles dissolve in the intracellular environment of triple negative breast cancer cells and cause apoptosis with intra-tumor heterogeneity

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Title: Correlative light-electron microscopy shows RGD-targeted ZnO nanoparticles dissolve in the intracellular environment of triple negative breast cancer cells and cause apoptosis with intra-tumor heterogeneity
Authors: Othman, BA
Greenwood, C
Abuelela, AF
Bharath, AA
Chen, S
Theodorou, I
Douglas, T
Uchida, M
Ryan, M
Merzaban, JS
Porter, AE
Item Type: Journal Article
Issue Date: 25-Apr-2016
Date of Acceptance: 17-Feb-2016
URI: http://hdl.handle.net/10044/1/30266
DOI: 10.1002/adhm.201501012
ISSN: 2192-2640
Publisher: Wiley
Start Page: 1310
End Page: 1325
Journal / Book Title: Advanced Healthcare Materials
Volume: 5
Issue: 11
Copyright Statement: © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This is the accepted version of the following article, which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1002/adhm.201501012/abstract
Sponsor/Funder: Kaust UK Ltd
Commission of the European Communities
Funder's Grant Number: N/A
ERC-2010-StG-20091028
Keywords: cellular targeting
cytotoxicity
integrin αvβ3 receptors
triple negative breast cancer cells
zinc oxide nanoparticles
Publication Status: Published
Appears in Collections:Materials
Bioengineering
Faculty of Natural Sciences
Faculty of Engineering