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A combined analysis of immunogenicity, antibody kinetics and vaccine efficacy from phase 2 trials of the RTS,S malaria vaccine

Title: A combined analysis of immunogenicity, antibody kinetics and vaccine efficacy from phase 2 trials of the RTS,S malaria vaccine
Authors: White, MT
Bejon, P
Olotu, A
Griffin, JT
Bojang, K
Lusingu, J
Salim, N
Abdulla, S
Otsyula, N
Agnandji, ST
Lell, B
Asante, KP
Owusu-Agyei, S
Mahama, E
Agbenyega, T
Ansong, D
Sacarlal, J
Aponte, JJ
Ghani, AC
Item Type: Journal Article
Issue Date: 10-Jul-2014
Date of Acceptance: 19-Jun-2014
URI: http://hdl.handle.net/10044/1/28331
DOI: https://dx.doi.org/10.1186/s12916-014-0117-2
ISSN: 1741-7015
Publisher: BioMed Central
Journal / Book Title: BMC Medicine
Volume: 12
Copyright Statement: © 2014 White et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Keywords: Science & Technology
Life Sciences & Biomedicine
Medicine, General & Internal
General & Internal Medicine
MEDICINE, GENERAL & INTERNAL
Malaria
Vaccine
Circumsporozoite protein
Antibody
RTS,S
Phase 2 clinical trials
Mathematical model
Clinical immunity
PLASMODIUM-FALCIPARUM INFECTION
RANDOMIZED-TRIAL
CONJUGATE VACCINE
AFRICAN CHILDREN
DOUBLE-BLIND
SAFETY
PROTECTION
INFANTS
RTS,S/AS02A
IMMUNIZATION
Publication Status: Published
Article Number: 117
Appears in Collections:School of Public Health