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4-Membered ring carbocations: a positive development in the synthesis of 3,3-disubstituted oxetanes and azetidines
File | Description | Size | Format | |
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2023_192.pdf | Published version | 546.57 kB | Adobe PDF | View/Open |
Title: | 4-Membered ring carbocations: a positive development in the synthesis of 3,3-disubstituted oxetanes and azetidines |
Authors: | Rojas, JJ Bull, J |
Item Type: | Journal Article |
Abstract: | 4-Membered heterocycles are low molecular weight polar scaffolds with intriguing potential for drug discovery. Despite their unquestionable value, methods to access such heterocycles remain scant. Here, we describe the generation of oxetane- and azetidine- benzylic carbocations as a general strategy to access valuable 3,3-disubstituted derivatives. |
Issue Date: | 26-Apr-2023 |
Date of Acceptance: | 27-Feb-2023 |
URI: | http://hdl.handle.net/10044/1/103373 |
DOI: | 10.2533/chimia.2023.192 |
ISSN: | 2673-2424 |
Publisher: | Schweizerische Chemische Gesellschaft |
Start Page: | 192 |
End Page: | 195 |
Journal / Book Title: | CHIMIA |
Volume: | 77 |
Issue: | 4 |
Copyright Statement: | © J. J. Rojas, J. A. Bull. This work is licensed under a Creative Commons Attribution 4.0 International License. The material may not be used for commercial purposes. The license is subject to the CHIMIA terms and conditions: (https://chimia.ch/chimia/about). The definitive version of this article is the electronic one that can be found at https://doi.org/10.2533/chimia.2023.192 |
Publication Status: | Published |
Online Publication Date: | 2023-04-26 |
Appears in Collections: | Chemistry Faculty of Natural Sciences |
This item is licensed under a Creative Commons License