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Age moderates the link between epilepsy and Self-rated Health (SRH)

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Title: Age moderates the link between epilepsy and Self-rated Health (SRH)
Authors: Kang, W
Item Type: Journal Article
Abstract: Epilepsy is one of the most severe neurological diseases that affect people around the globe. Self-rated health (SRH) refers to one’s subjective evaluation of their own health and is associated with various outcomes such as morbidity and mortality. Thus, understanding the association between epilepsy and SRH is of great importance. Moreover, SRH generally decreases with age. The aim of the current study is to test whether age moderates the link between epilepsy and SRH. The current study used a hierarchical regression and three multiple regressions to analyze the associations between epilepsy and SRH in 529 epilepsy patients and 46,978 healthy controls from the United Kingdom. The current study found that age significantly moderates the association between epilepsy and SRH. Specifically, epilepsy status was negatively related to SRH in young people (b = −0.69, p < 0.001, 95% C.I. [−0.84, −0.54]), more strongly in middle-aged adults (b = −0.81, p < 0.001, 95% C.I. [−0.95, −0.66]), and most strongly in older adults (b = −0.89, p < 0.001, 95% C.I. [−1.09, −0.69]). The current study may imply that older adults need more attention in terms of their SRH, which is closely associated with outcomes. Clinicians and health professionals should come up with ways that improve SRH in people with epilepsy, especially for older adults with epilepsy.
Issue Date: 19-Oct-2022
Date of Acceptance: 18-Oct-2022
URI: http://hdl.handle.net/10044/1/101041
DOI: 10.3390/jcm11206175
ISSN: 2077-0383
Publisher: MDPI AG
Journal / Book Title: Journal of Clinical Medicine
Volume: 11
Issue: 20
Copyright Statement: © 2022 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Publication Status: Published
Article Number: ARTN 6175
Appears in Collections:Department of Brain Sciences



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