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Coffee intake and incidence of erectile dysfunction
File(s)
Author(s)
Lopez, David S
Liu, Lydia
Rimm, Eric B
Tsilidis, Konstantinos K
de Oliveira Otto, Marcia
Type
Journal Article
Abstract
Coffee intake is suggested to have a positive role against chronic diseases. Yet, the role of coffee in urological diseases such as erectile dysfunction (ED) remains unclear. Thus, we investigated the association of coffee intake with incidence of ED.A prospective analysis of 21,403 men aged 40-75 years old was conducted using the Health Professionals Follow-Up Study. Total coffee, regular and decaffeinated coffee intakes were self-reported on food-frequency questionnaires. ED was assessed by means of questionnaires in 2000, 2004 and 2008. Multivariable adjusted Cox proportional hazards models were used to compute hazard ratios (HR) for incident ED (N = 7,298). No significant differences were identified for incident ED after comparing highest (≥ 4 cups/day) with lowest category (0 cups/day) of total- (HR = 1.00; 95% CI: 0.90 - 1.11) and regular- coffee intakes (HR = 1.00; 95% CI: 0.89 - 1.13). For decaffeinated coffee intake, after comparing the highest category with lowest category, we found a 37% increased risk of ED (HR = 1.37; 95% CI = 1.08-1.73) with a significant trend (Ptrend = 0.02). Stratified analyses showed an association among current smokers (Ptrend = 0.005).Overall, long-term coffee intake was not associated with risk of ED in a prospective cohort study.
Date Issued
2018-05-01
Date Acceptance
2017-08-16
Citation
American Journal of Epidemiology, 2018, 187 (5), pp.951-959
URI
DOI
ISSN
1476-6256
Publisher
Oxford University Press (OUP)
Start Page
951
End Page
959
Journal / Book Title
American Journal of Epidemiology
Volume
187
Issue
5
Copyright Statement
© The Author(s) 2018. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
Identifier
https://www.ncbi.nlm.nih.gov/pubmed/29020139
PII: 4093018
Subjects
coffee
decaffeinated coffee
erectile dysfunction
Publication Status
Published
Coverage Spatial
United States
Date Publish Online
2017-08-23