Neonates and COVID-19: state of the art Neonatal Sepsis series
File(s)
Author(s)
Type
Journal Article
Abstract
The SARS-CoV-2 pandemic has had a significant impact worldwide, particularly in middle- and low-income countries. While this impact has been well-recognized in certain age groups, the effects, both direct and indirect, on the neonatal population remain largely unknown. There are placental changes associated, though the contributions to maternal and fetal illness have not been fully determined. The rate of premature delivery has increased and SARS-CoV-2 infection is proportionately higher in premature neonates, which appears to be related to premature delivery for maternal reasons rather than an increase in spontaneous preterm labor. There is much room for expansion, including long-term data on outcomes for affected babies. Though uncommon, there has been evidence of adverse events in neonates, including Multisystem Inflammatory Syndrome in Children, associated with COVID-19 (MIS-C). There are recommendations for reduction of viral transmission to neonates, though more research is required to determine the role of passive immunization of the fetus via maternal vaccination. There is now considerable evidence suggesting that the severe visitation restrictions implemented early in the pandemic have negatively impacted the care of the neonate and the experiences of both parents and healthcare professionals alike. Ongoing collaboration is required to determine the full impact, and guidelines for future management.
Date Issued
2022-01-01
Date Acceptance
2021-11-05
Citation
Pediatric Research, 2022, 91 (2), pp.432-439
ISSN
0031-3998
Publisher
Springer Nature [academic journals on nature.com]
Start Page
432
End Page
439
Journal / Book Title
Pediatric Research
Volume
91
Issue
2
Copyright Statement
Copyright © 2021, The Author(s), under exclusive licence to the International Pediatric Research Foundation, Inc.
Identifier
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000735341200003&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
Subjects
ANTIBODIES
CHILDREN
CORONAVIRUS DISEASE 2019
HEALTH-CARE
HOSPITALIZED PREGNANT-WOMEN
IMMUNE-SYSTEM
LESSONS
Life Sciences & Biomedicine
MOTHERS
OUTCOMES
Pediatrics
SARS-COV-2 INFECTION
Science & Technology
Publication Status
Published
Date Publish Online
2021-12-28