A 38-year-old Nigerian man with no significant past medical history presented with a discharging lesion on the plantar aspect of his left foot, with a provisional diagnosis of a viral wart. Cutaneotrichosporon debeurmannianum was isolated from deep tissue and identified by sequencing the internal transcribed spacer region ITS-1 and the D1-2 fragment of the 28S rDNA gene. Histopathological examination showed psoriasiform hyperplasia with dermal scarring and scanty inflammation. The patient was successfully treated with a course of voriconazole. C. debeurmannianum exhibited high MIC values for echinocandin antifungals in vitro, however MICs to triazoles and amphotericin B remained low. To our knowledge, this is the first report of a subcutaneous mycotic cyst associated with this newly described yeast in an immunocompetent man.