Update on clinical aspects of chronic obstructive pulmonary disease

File Description SizeFormat 
Update-on-Clinical-Aspects-of-Chronic-Obstructive.pdfFile embargoed until 26 March 2020378.82 kBAdobe PDF    Request a copy
Title: Update on clinical aspects of chronic obstructive pulmonary disease
Authors: Celli, BR
Wedzicha, JA
Item Type: Journal Article
Abstract: Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide; COPD led to 3.2 million deaths in 2017, a toll expected to reach 4.4 million yearly by 2040.1,2 With a worldwide prevalence of 10.1%, COPD afflicts many people in low-income, middle-income, and wealthy countries (Figure 1), and years of life lost prematurely increased 13.2% between 2007 and 2017.1 Although COPD has traditionally been considered a disease that affects men, in some countries, the prevalence and associated mortality are higher among women than among men. In this review, we update the clinical face of COPD, concentrating on the pulmonary aspects of the disease, which also affects many other organ systems. The pathogenesis of COPD is discussed in a companion article by Agustí and Hogg in this issue of the Journal,3 and the review of muco-obstructive lung diseases in a recent issue of the Journal4 complements this article.
Issue Date: 26-Sep-2019
Date of Acceptance: 1-Sep-2019
URI: http://hdl.handle.net/10044/1/74110
DOI: https://doi.org/10.1056/NEJMra1900500
ISSN: 0028-4793
Publisher: Massachusetts Medical Society
Start Page: 1257
End Page: 1266
Journal / Book Title: New England Journal of Medicine
Volume: 381
Issue: 13
Copyright Statement: © 2019 Massachusetts Medical Society. All rights reserved.
Keywords: Science & Technology
Life Sciences & Biomedicine
Medicine, General & Internal
General & Internal Medicine
AIR-FLOW OBSTRUCTION
ACUTE EXACERBATIONS
NORMAL SPIROMETRY
RISK-FACTORS
COPD
OUTCOMES
SMOKERS
FLUTICASONE
PREVENTION
MANAGEMENT
Adrenergic beta-Agonists
Humans
Muscarinic Antagonists
Oxygen Inhalation Therapy
Prevalence
Pulmonary Disease, Chronic Obstructive
Humans
Pulmonary Disease, Chronic Obstructive
Adrenergic beta-Agonists
Muscarinic Antagonists
Oxygen Inhalation Therapy
Prevalence
Science & Technology
Life Sciences & Biomedicine
Medicine, General & Internal
General & Internal Medicine
AIR-FLOW OBSTRUCTION
ACUTE EXACERBATIONS
NORMAL SPIROMETRY
RISK-FACTORS
COPD
OUTCOMES
SMOKERS
FLUTICASONE
PREVENTION
MANAGEMENT
General & Internal Medicine
11 Medical and Health Sciences
Publication Status: Published
Embargo Date: 2020-03-26
Online Publication Date: 2019-09-26
Appears in Collections:National Heart and Lung Institute
Airway Disease



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Creative Commons