High-contrast 3D in vivo microvascular imaging using scanning 2D ultrasound and acoutic sub-aperture processing (ASAP)

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Title: High-contrast 3D in vivo microvascular imaging using scanning 2D ultrasound and acoutic sub-aperture processing (ASAP)
Authors: Hau Leow, C
Bush, NL
Stanziola, A
Braga, M
Shah, A
Hemández-Gil, J
Long, NJ
Aboagye, EO
Bamber, JC
Tang, MX
Item Type: Conference Paper
Abstract: Non-invasive techniques for microvascular environment assessment are invaluable for clinical diagnosis and treatment monitoring. We recently developed a super contrast processing to suppress noise background in ultrafast Power Doppler, known an acoustic sub-aperture processing (ASAP), and demonstrate using 2D contrast enhance ultrasound. However, 2D imaging is insufficient to represent the 3D complex vascular environment. We therefore extend our study to demonstrate the feasibility of our technique for volumetric imaging. A pseudo-3D imaging technique was developed and demonstrated using a research system and preclinical transducer. A mouse liver was scanned using 2D ultrafast ultrasound and a mechanical translation stage. Initial results not only demonstrated a substantial noise reduction in 2D vascular images using ASAP, but also a high contrast volumetric rendering of a mouse liver. Our technique is ready for clinical use to provide better evaluation of angiogenesis.
Issue Date: 25-Feb-2019
Date of Acceptance: 22-Oct-2018
URI: http://hdl.handle.net/10044/1/72937
DOI: https://dx.doi.org/10.1109/ULTSYM.2018.8579675
ISSN: 1948-5719
Publisher: IEEE
Journal / Book Title: IEEE International Ultrasonics Symposium, IUS
Copyright Statement: © 2018 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Sponsor/Funder: Cancer Research UK
Funder's Grant Number: 22353
Conference Name: IEEE International Ultrasonics Symposium, IUS. 2018
Publication Status: Published
Start Date: 2018-10-22
Finish Date: 2018-10-25
Conference Place: Kobe, Japan
Appears in Collections:Bioengineering
Division of Surgery
Catalysis and Advanced Materials
Division of Cancer
Faculty of Medicine
Faculty of Natural Sciences

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