The role of socioeconomic status in the association of lung function and air pollution - A pooled analysis of three adult ESCAPE cohorts
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Title: | The role of socioeconomic status in the association of lung function and air pollution - A pooled analysis of three adult ESCAPE cohorts |
Authors: | Keidel, D Maria Anto, J Basagana, X Bono, R Burte, E Carsin, A-E Forsberg, B Fuertes, E Galobardes, B Heinrich, J De Hoogh, K Jarvis, D Kunzli, N Leynaert, B Marcon, A Le Moual, N De Nazelle, A Schindler, C Siroux, V Stempfelet, M Sunyer, J Temam, S Tsai, M-Y Varraso, R Jacquemin, B Probst-Hensch, N |
Item Type: | Journal Article |
Abstract: | Ambient air pollution is a leading environmental risk factor and its broad spectrum of adverse health effects includes a decrease in lung function. Socioeconomic status (SES) is known to be associated with both air pollution exposure and respiratory function. This study assesses the role of SES either as confounder or effect modifier of the association between ambient air pollution and lung function. Cross-sectional data from three European multicenter adult cohorts were pooled to assess factors associated with lung function, including annual means of home outdoor NO2. Pre-bronchodilator lung function was measured according to the ATS-criteria. Multiple mixed linear models with random intercepts for study areas were used. Three different factors (education, occupation and neighborhood unemployment rate) were considered to represent SES. NO2 exposure was negatively associated with lung function. Occupation and neighborhood unemployment rates were not associated with lung function. However, the inclusion of the SES-variable education improved the models and the air pollution-lung function associations got slightly stronger. NO2 associations with lung function were not substantially modified by SES-variables. In this multicenter European study we could show that SES plays a role as a confounder in the association of ambient NO2 exposure with lung function. |
Issue Date: | 1-Jun-2019 |
Date of Acceptance: | 24-May-2019 |
URI: | http://hdl.handle.net/10044/1/72127 |
DOI: | https://doi.org/10.3390/ijerph16111901 |
ISSN: | 1660-4601 |
Publisher: | MDPI |
Journal / Book Title: | International Journal of Environmental Research and Public Health |
Volume: | 16 |
Issue: | 11 |
Copyright Statement: | © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
Keywords: | Science & Technology Life Sciences & Biomedicine Environmental Sciences Public, Environmental & Occupational Health Environmental Sciences & Ecology Europe socioeconomic position air pollution environmental equality lung function RESPIRATORY HEALTH NO2 EXPOSURE QUALITY PM10 MORTALITY BENEFITS DECLINE EUROPE AREAS Europe air pollution environmental equality lung function socioeconomic position Science & Technology Life Sciences & Biomedicine Environmental Sciences Public, Environmental & Occupational Health Environmental Sciences & Ecology Europe socioeconomic position air pollution environmental equality lung function RESPIRATORY HEALTH NO2 EXPOSURE QUALITY PM10 MORTALITY BENEFITS DECLINE EUROPE AREAS Toxicology MD Multidisciplinary |
Publication Status: | Published |
Article Number: | 1901 |
Online Publication Date: | 2019-05-29 |
Appears in Collections: | Infectious Disease Epidemiology National Heart and Lung Institute Centre for Environmental Policy Faculty of Natural Sciences Epidemiology, Public Health and Primary Care |