Mortality from Ischaemic Heart Disease: analysis of data from the World Health Organization and coronary artery disease risk factors from NCD-RisC

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Title: Mortality from Ischaemic Heart Disease: analysis of data from the World Health Organization and coronary artery disease risk factors from NCD-RisC
Authors: Nowbar, AN
Gitto, M
Howard, J
Francis, D
Al-Lamee, R
Item Type: Journal Article
Abstract: Background Ischemic heart disease (IHD) has been considered the top cause of mortality globally. However, countries differ in their rates and there have been changes over time. Methods and Results We analyzed mortality data submitted to the World Health Organization from 2005 to 2015 by individual countries. We explored patterns in relationships with age, sex, and income and calculated age-standardized mortality rates for each country in addition to crude death rates. In 5 illustrative countries which provided detailed data, we analyzed trends of mortality from IHD and 3 noncommunicable diseases (lung cancer, stroke, and chronic lower respiratory tract diseases) and examined the simultaneous trends in important cardiovascular risk factors. Russia, United States, and Ukraine had the largest absolute numbers of deaths among the countries that provided data. Among 5 illustrative countries (United Kingdom, United States, Brazil, Kazakhstan, and Ukraine), IHD was the top cause of death, but mortality from IHD has progressively decreased from 2005 to 2015. Age-standardized IHD mortality rates per 100 000 people per year were much higher in Ukraine (324) and Kazakhstan (97) than in United States (60), Brazil (54), and the United Kingdom (46), with much less difference in other causes of death. All 5 countries showed a progressive decline in IHD mortality, with a decline in smoking and hypertension and in all cases a rise in obesity and type II diabetes mellitus. Conclusions IHD remains the single largest cause of death in countries of all income groups. Rates are different between countries and are falling in most countries, indicating great potential for further gains. On the horizon, future improvements may become curtailed by increasing hypertension in some developing countries and more importantly global growth in obesity.
Issue Date: 1-Jun-2019
Date of Acceptance: 13-May-2019
ISSN: 1941-7705
Publisher: American Heart Association
Journal / Book Title: Circulation: Cardiovascular Quality and Outcomes
Volume: 12
Issue: 6
Copyright Statement: © 2019 The Authors. Circulation: Cardiovascular Quality and Outcomes is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Sponsor/Funder: Wellcome Trust
Imperial College Healthcare NHS Trust- BRC Funding
Funder's Grant Number: PS3162_WHCP
Keywords: Cardiovascular System & Hematology
1102 Cardiorespiratory Medicine and Haematology
1117 Public Health and Health Services
Publication Status: Published
Article Number: e005375
Appears in Collections:National Heart and Lung Institute
Faculty of Medicine

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