Iodination of terminal alkynes using KI/CuSO4 – A facile method with potential for radio-iodination

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Title: Iodination of terminal alkynes using KI/CuSO4 – A facile method with potential for radio-iodination
Authors: Ferris, T
Carroll, L
Mease, RC
Spivey, AC
Aboagye, EO
Item Type: Journal Article
Abstract: Herein, we report an efficient new method for the iodination of terminal alkynes using stoichiometric KI and CuSO4 in a mix of acetonitrile and acetate buffer that holds promise for further development into a method for radio-iodination.
Issue Date: 28-Mar-2019
Date of Acceptance: 22-Feb-2019
URI: http://hdl.handle.net/10044/1/68407
DOI: https://dx.doi.org/10.1016/j.tetlet.2019.02.041
ISSN: 0040-4039
Publisher: Elsevier BV
Start Page: 936
End Page: 939
Journal / Book Title: Tetrahedron Letters
Volume: 60
Issue: 13
Copyright Statement: © 2019 Elsevier Ltd. All rights reserved. This manuscript is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence http://creativecommons.org/licenses/by-nc-nd/4.0/
Sponsor/Funder: Cancer Research UK
Funder's Grant Number: C2536/A16584
Keywords: 0305 Organic Chemistry
Organic Chemistry
Publication Status: Published
Embargo Date: 2020-02-23
Online Publication Date: 2019-02-23
Appears in Collections:Division of Surgery
Chemistry
Division of Cancer
Faculty of Medicine
Faculty of Natural Sciences



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