The Synthetic Genome Summer Course

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Title: The Synthetic Genome Summer Course
Authors: Blount, B
Ellis, T
Item Type: Journal Article
Abstract: The Synthetic Genome Summer Course was convened with the aim of teaching a wide range of researchers the theory and practical skills behind recent advances in synthetic biology and synthetic genome science, with a focus on Sc2.0, the synthetic yeast genome project. Through software workshops, tutorials and research talks from leading members of the field, the 30 attendees learnt about relevant principles and techniques that they were then able to implement first-hand in laboratory-based practical sessions. Participants SCRaMbLEd semi-synthetic yeast strains to diversify heterologous pathways, used automation to build combinatorial pathway libraries and used CRISPR to debug fitness defects caused by synthetic chromosome design changes. Societal implications of synthetic chromosomes were explored and industrial stakeholders discussed synthetic biology from a commercial standpoint. Over the 5 days, participants gained valuable insight and acquired skills to aid them in future synthetic genome research.
Issue Date: 1-Jan-2019
Date of Acceptance: 24-Nov-2018
ISSN: 2397-7000
Publisher: Oxford University Press (OUP)
Journal / Book Title: Synthetic Biology
Volume: 3
Issue: 1
Copyright Statement: © The Author(s) 2018. Published by Oxford University Press.This is an Open Access article distributed under the terms of the Creative Commons Attribution License (,which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
Sponsor/Funder: Biotechnology and Biological Sciences Research Council (BBSRC)
Biotechnology and Biological Sciences Research Council (BBSRC)
Funder's Grant Number: BB/K006290/1
Publication Status: Published
Open Access location:
Online Publication Date: 2018-11-27
Appears in Collections:Bioengineering

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