Diversification of characteristics related to regional endothermy in Thunnus tunas

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Title: Diversification of characteristics related to regional endothermy in Thunnus tunas
Authors: Ciezarek, A
Osbourne, O
Shipley, ON
Brooks, EJ
Tracey, S
McAllister, J
Gardner, L
Sternberg, MJE
Block, B
Savolainen, V
Item Type: Journal Article
Abstract: Birds, mammals, and certain fishes, including tunas, opahs and lamnid sharks, are endothermic, conserving internally generated, metabolic heat to maintain body or tissue temperatures above that of the environment. Bluefin tunas, among the most threatened, but commercially important, fishes worldwide are renowned regional endotherms, maintaining elevated temperatures of the oxidative locomotor muscle, viscera, brain and eyes, and occupying cold, productive high-latitude waters. Less cold-tolerant tuna, such as yellowfin, by contrast, remain in warm-temperate to tropical waters year-round, reproducing more rapidly than temperate bluefin tuna. Thereby, they are more resilient to fisheries, whereas bluefins have declined steeply. Despite the importance of these traits to not only fisheries, but response to climate change, little is known of the genetic processes underlying the diversification of tuna. In collecting and analysing sequence data across 29,556 genes, we found that parallel selection on standing genetic variation has driven the evolution of endothermy in bluefin tunas. This includes two shared substitutions in genes encoding glycerol-3 phosphate dehydrogenase, an enzyme which underlies thermogenesis in bumblebees and mammals, as well as four genes involved in the Krebs cycle, oxidative phosphorylation, β-oxidation and superoxide removal. Using phylogenetic techniques, we further illustrate that the eight Thunnus species are genetically distinct, but found evidence of mitochondrial genome introgression across two species. Phylogeny-based metrics highlight conservation needs for some of these species.
Date of Acceptance: 5-Oct-2018
URI: http://hdl.handle.net/10044/1/65244
ISSN: 1537-1719
Publisher: Oxford University Press (OUP)
Journal / Book Title: Molecular Biology and Evolution
Copyright Statement: This paper is embargoed until 12 months after publication.
Sponsor/Funder: Natural Environment Research Council (NERC)
The Leverhulme Trust
Funder's Grant Number: NE/M015742/1
Keywords: 0604 Genetics
0603 Evolutionary Biology
0601 Biochemistry And Cell Biology
Evolutionary Biology
Publication Status: Accepted
Appears in Collections:Faculty of Natural Sciences

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