Electrophysiological testing in concussion: A guide to clinical applications

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Title: Electrophysiological testing in concussion: A guide to clinical applications
Author(s): Papathanasiou, ES
Cronin, T
Seemungal, B
Sandhu, J
Item Type: Journal Article
Abstract: The diagnosis of mild traumatic brain injury in concussion is difficult since it is often unwitnessed, the patient’s recall is unreliable and initial clinical examination is often unrevealing, correlating poorly with the extent of brain injury. At present, there are no objective biomarkers of mild traumatic brain injury in concussion. Thus, a sensitive gold standard test is required to enable the effective and safe triage of patients who present to the acute services. As well as triage, objective monitoring of patients’ recovery over time and separate from clinical features that patients may develop following the injury (e.g. depression and migraine) is also needed. In contrast to neuroimaging, which is widely used to investigate traumatic brain injury patients, electrophysiology is readily available, is cheap and there are internationally recognized standardised methodologies. Herein, we review the existing literature on electrophysiological testing in concussion and mild traumatic brain injury; specifically, electroencephalogram, polysomnography, brainstem auditory evoked potentials, electro- and videonystagmography, vestibular evoked myogenic potentials, visually evoked potentials, somatosensory evoked potentials and transcranial magnetic stimulation.
Publication Date: 10-Dec-2018
Date of Acceptance: 26-Sep-2018
URI: http://hdl.handle.net/10044/1/65051
DOI: https://dx.doi.org/10.1177/2059700218812634
ISSN: 2059-7002
Publisher: SAGE Publications
Journal / Book Title: Journal of Concussion
Volume: 2
Sponsor/Funder: Medical Research Council (MRC)
National Institute for Health Research
Imperial Health Charity
Imperial Health Charity
Funder's Grant Number: MR/P006493/1
RDA26
RF18\100033
GG1516\100028
Copyright Statement: © 2018 The Author(s). This article is distributed under the terms of the Creative Commons Attribution- NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
Publication Status: Published
Open Access location: https://journals.sagepub.com/doi/pdf/10.1177/2059700218812634
Online Publication Date: 2018-12-10
Appears in Collections:Department of Medicine



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