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Results 1-10 of 16
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Issue DateTitleAuthor(s)
1-Dec-2009A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replicationEvrin, C; Clarke, P; Zech, J; Lurz, R; Sun, J, et al
13-Feb-2017Structural basis of MCM2-7 replicative helicase loading by ORC-Cdc6 and Cdt1Yuan, Z; Riera, A; Bai, L; Sun, J; Nandi, S, et al
27-May-2016Replicating repetitive DNATognetti, S; Speck, C; Wellcome Trust; Biotechnology and Biological Sciences Research Council (BBSRC)
6-May-2016Exceeding the limits - Cdc45 overexpression turns badSpeck, C; Wellcome Trust; Biotechnology and Biological Sciences Research Council (BBSRC)
15-Oct-2014Structural and mechanistic insights into Mcm2-7 double-hexamer assembly and function.Sun, J; Fernandez-Cid, A; Riera, A; Tognetti, S; Yuan, Z, et al
25-Oct-2017Cryo-EM structure of Mcm2-7 double-hexamer on DNA suggests a lagging strand DNA extrusion modelNoguchi, Y; Yuan, Z; Bai, L; Schneider, S; Zhao, G, et al
12-Oct-2014Switch on the engine: how the eukaryotic replicative helicase MCM2–7 becomes activatedTognetti, S; Riera, A; Speck, C
23-May-2013An ORC/Cdc6/MCM2-7 Complex Is Formed in a Multistep Reaction to Serve as a Platform for MCM Double-Hexamer AssemblyFernandez-Cid, A; Riera, A; Tognetti, S; Herrera, MC; Samel, S, et al
29-Jul-2008The architecture of the DNA replication origin recognition complex in Saccharomyces cerevisiae.Chen, Z; Speck, C; Wendel, P; Tang, C; Stillman, B, et al
25-Aug-2015Cdc6 ATPase activity disengages Cdc6 from the pre-replicative complex to promote DNA replicationSpeck, C