Improving temporal resolution and speed sensitivity of laser speckle contrast analysis imaging based on noise reduction with an anisotropic diffusion filter

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Title: Improving temporal resolution and speed sensitivity of laser speckle contrast analysis imaging based on noise reduction with an anisotropic diffusion filter
Authors: Song, L
Wang, X
Zhang, R
Zhang, K
Zhou, Z
Elson, DS
Item Type: Journal Article
Abstract: The fluctuation of contrast caused by statistical noise degenerates the temporal/spatial resolution of laser speckle contrast imaging (LSCI) and limits the maximum speed when imaging. In this study, we investigated the application of the anisotropic diffusion filter (ADF) to temporal LSCI and found that the edge magnitude parameter of the ADF can be determined by the mean of the contrast image. Because the edge magnitude parameter is usually denoted as K, we term this the K-constant ADF (KC-ADF) and show that temporal sensitivity is improved when imaging because of the enhanced signal-to-noise ratio when using the KC-ADF in small-animal experiments. The cardiac cycle of a rat as high as 390 bpm can be imaged with an industrial camera.
Issue Date: 1-Jul-2018
Date of Acceptance: 15-May-2018
URI: http://hdl.handle.net/10044/1/60799
DOI: https://dx.doi.org/10.1088/2040-8986/aac4be
ISSN: 2040-8978
Publisher: IOP PUBLISHING LTD
Journal / Book Title: JOURNAL OF OPTICS
Volume: 20
Issue: 7
Copyright Statement: © 2018 IOP Publishing Ltd. This is an author-created, un-copyedited version of an article accepted for publication in Journal of Optics. IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The definitive publisher authenticated version is available online at https://dx.doi.org/10.1088/2040-8986/aac4be
Sponsor/Funder: Commission of the European Communities
Funder's Grant Number: 242991
Keywords: Science & Technology
Physical Sciences
Optics
laser speckle contrast imaging
temporal resolution
anisotropic diffusion filter
signal-to-noise ratio
speed sensitivity
CEREBRAL-BLOOD-FLOW
ULTRASOUND IMAGES
EDGE-DETECTION
ENHANCEMENT
SCALE
SIZE
0205 Optical Physics
0906 Electrical And Electronic Engineering
Publication Status: Published
Article Number: ARTN 075301
Online Publication Date: 2018-05-31
Appears in Collections:Division of Surgery
Faculty of Medicine



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