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Use of biomedical photonics in gynecological surgery: a uterine transplantation model

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Title: Use of biomedical photonics in gynecological surgery: a uterine transplantation model
Authors: Saso, S
Clancy, NT
Jones, BP
Bracewell-Milnes, T
Al-Memar, M
Cannon, EM
Ahluwalia, S
Yazbek, J
Thum, M-Y
Bourne, T
Elson, DS
Smith, JR
Ghaem-Maghami, S
Item Type: Journal Article
Abstract: Aim: Uterine transplantation (UTx) has been proposed as a treatment for permanent absolute uterine factor infertility. The study aims were to compare pulse oximetry and multispectral imaging (MSI), for intraoperative tracking of uterine oxygen saturation in animal UTx models (rabbit and sheep). Results/methodology: Imaging results confirmed the re-establishment of adequate perfusion in the transplanted organ after surgery. Comparison of oxygen saturation values between the pre-UTx donor and post-UTx recipient, and pre-UTx and post-UTx recipient reveals a statistically significant decrease in saturation levels post-UTx. Conclusion: The use of MSI is the first case in gynecology and has demonstrated promise of possible future human use. MSI technique has advantages over pulse oximetry - it provides spatial information in a real-time, noncontact manner.
Issue Date: 1-Apr-2018
Date of Acceptance: 3-Jan-2018
URI: http://hdl.handle.net/10044/1/58691
DOI: https://dx.doi.org/10.4155/fsoa-2017-0129
ISSN: 2056-5623
Publisher: Future Science
Start Page: FSO286
End Page: FSO286
Journal / Book Title: Future Science OA
Volume: 4
Issue: 4
Copyright Statement: © 2018 The Author(s). This work is licensed under the Creative Commons Attribution 4.0 License. To view a copy of this license, visit http://creativecomm ons.org/licenses/by/4.0/
Sponsor/Funder: Engineering & Physical Science Research Council (EPSRC)
Commission of the European Communities
Deutsche Forschungsgemeinschaft ( German Research
Funder's Grant Number: EP/E06342X/1
242991
637960
Keywords: optical imaging
oxygen saturation
surgical imaging
tissue perfusion
uterine transplantation
Publication Status: Published
Conference Place: England
Online Publication Date: 2018-02-06
Appears in Collections:Division of Surgery
Faculty of Medicine



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