Catalysis in flow: nickel-catalyzed synthesis of primary amines from alcohols and NH3

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Title: Catalysis in flow: nickel-catalyzed synthesis of primary amines from alcohols and NH3
Author(s): Keung Leung, AY
Hellgardt, K
Leung, A
Hii, KM
Item Type: Journal Article
Abstract: A highly selective synthesis of primary amines from alcohols and NH3 was achieved on using a commercially available Ni catalyst, without adding H2. Using a continuous flow reaction platform, the amination of aliphatic alcohols can be achieved in good yields and selectivities, as the accumulation of water byproduct can be removed. Competitive formation of the nitrile side-product was suppressed when the catalyst was prereduced. Modes of catalyst deactivation were also briefly examined.
Publication Date: 5-Mar-2018
Date of Acceptance: 19-Feb-2018
URI: http://hdl.handle.net/10044/1/57850
DOI: https://dx.doi.org/10.1021/acssuschemeng.8b00338
ISSN: 2168-0485
Publisher: American Chemical Society
Start Page: 5479
End Page: 5484
Journal / Book Title: ACS Sustainable Chemistry and Engineering
Volume: 6
Issue: 4
Copyright Statement: © 2018 American Chemical Society.
Keywords: Science & Technology
Physical Sciences
Technology
Chemistry, Multidisciplinary
GREEN & SUSTAINABLE SCIENCE & TECHNOLOGY
Engineering, Chemical
Chemistry
Science & Technology - Other Topics
Engineering
Atom-efficient
Continuous flow process
Hydrogen-borrowing
Nickel
Selective
Primary amines
N-ALKYLATION
HYDROXIDE CATALYSTS
SECONDARY-AMINES
DIRECT AMINATION
AMMONIA
FORMULATIONS
COMPLEXES
EFFICIENT
Publication Status: Published
Embargo Date: 2019-03-05
Appears in Collections:Faculty of Engineering
Chemistry
Catalysis and Advanced Materials
Chemical Engineering
Faculty of Natural Sciences



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