Technical Note: Error metrics for estimating the accuracy of needle/instrument placement during transperineal MR/US-guided prostate interventions

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Title: Technical Note: Error metrics for estimating the accuracy of needle/instrument placement during transperineal MR/US-guided prostate interventions
Author(s): Bonmati, E
Hu, Y
Villarini, B
Rodell, R
Martin, P
Han, L
Donaldson, I
Ahmed, HU
Moore, CM
Emberton, M
Barratt, DC
Item Type: Journal Article
Abstract: PURPOSE: Image-guided systems that fuse magnetic resonance imaging (MRI) with three-dimensional (3D) ultrasound (US) images for performing targeted prostate needle biopsy and minimally-invasive treatments for prostate cancer are of increasing clinical interest. To date, a wide range of different accuracy estimation procedures and error metrics have been reported, which makes comparing the performance of different systems difficult. METHODS: A set of 9 measures are presented to assess the accuracy of MRI-US image registration, needle positioning, needle guidance, and overall system error, with the aim of providing a methodology for estimating the accuracy of instrument placement using a MR/US-guided transperineal approach. RESULTS: Using the SmartTarget fusion system, an MRI-US image alignment error was determined to be 2.0±1.0 mm (mean ± SD), and an overall system instrument targeting error of 3.0±1.2 mm. Three needle deployments for each target phantom lesion was found to result in a 100% lesion hit rate and a median predicted cancer core length of 5.2 mm. CONCLUSIONS: The application of a comprehensive, unbiased validation assessment for MR/TRUS guided systems can provide useful information on system performance for quality assurance and system comparison. Furthermore, such an analysis can be helpful in identifying relationships between these errors, providing insight into the technical behaviour of these systems.
Publication Date: 1-Apr-2018
Date of Acceptance: 1-Feb-2018
URI: http://hdl.handle.net/10044/1/57615
DOI: https://dx.doi.org/10.1002/mp.12814
ISSN: 0094-2405
Publisher: Wiley
Start Page: 1408
End Page: 1414
Journal / Book Title: Medical Physics
Volume: 45
Issue: 4
Copyright Statement: © 2018 American Association of Physicists in Medicine. This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1002/mp.12814
Keywords: Science & Technology
Life Sciences & Biomedicine
Radiology, Nuclear Medicine & Medical Imaging
accuracy validation
focal therapy
image-guided interventions
needle placement
prostate cancer
targeted biopsy
TRANSRECTAL ULTRASOUND
BIOPSY SYSTEM
NEEDLE PLACEMENT
FUSION
GUIDANCE
REGISTRATION
PHANTOM
MR
accuracy validation
focal therapy
image-guided interventions
needle placement
prostate cancer
targeted biopsy
Accuracy Validation
Focal Therapy
Image-guided Interventions
Needle Placement
Prostate Cancer
Targeted Biopsy
Publication Status: Published
Conference Place: United States
Embargo Date: 2019-02-14
Online Publication Date: 2018-02-14
Appears in Collections:Division of Surgery
Faculty of Medicine



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