Multi-Frame Rate Plane Wave Contrast-Enhance Ultrasound Imaging for Tumour Vasculature Imaging and Perfusion Quantification

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Title: Multi-Frame Rate Plane Wave Contrast-Enhance Ultrasound Imaging for Tumour Vasculature Imaging and Perfusion Quantification
Authors: Leow, CH
Marta, B
Stanziola, A
Hernandez-Gil, J
Long, NJ
Aboagye, EO
Tang, M-X
Item Type: Conference Paper
Abstract: A multi-frame rate plane wave imaging strategy is developed to simultaneously image tumor vasculature and quantify tumor perfusion. Customised imaging sequences interleaving a short but high frame rate (HFR) plane wave imaging sequence with a long but low frame rate imaging (LFR) sequence were implemented using a programmable ultrasound research platform. The results from a spatio-temporal coherence processing technique of ours demonstrated a significant improvement in the SNR and vasculature contrast when compared with the existing ultrafast Power Doppler (PD) using the same data. Initial perfusion quantification using LFR imaging was also demonstrated. Mean time intensity curve and some parametric measures were generated. Combining both structural and functional perfusion imaging using the multiframe rate sequences, a better evaluation of the tumour angiogenesis can be assessed.
Issue Date: 2-Nov-2017
Date of Acceptance: 1-Sep-2017
ISSN: 1948-5719
Publisher: IEEE
Copyright Statement: © 2017 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
Sponsor/Funder: Cancer Research UK
Funder's Grant Number: C53470/A22353
Conference Name: IEEE International Ultrasonics Symposium (IUS)
Keywords: Science & Technology
Physical Sciences
Engineering, Electrical & Electronic
Physics, Applied
Molecular imaging
microvascular flow and perfusion
plane wave imaging
microbubbles contrast agents
Publication Status: Published
Start Date: 2017-09-06
Finish Date: 2017-09-09
Conference Place: Washington, DC
Appears in Collections:Faculty of Engineering
Division of Surgery
Catalysis and Advanced Materials
Division of Cancer
Faculty of Medicine
Faculty of Natural Sciences

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