Carbohydrate-Responsive Element-Binding Protein (ChREBP) Is a Negative Regulator of ARNT/HIF-1 beta Gene Expression in Pancreatic Islet beta-Cells

Title: Carbohydrate-Responsive Element-Binding Protein (ChREBP) Is a Negative Regulator of ARNT/HIF-1 beta Gene Expression in Pancreatic Islet beta-Cells
Authors: Noordeen, NA
Khera, TK
Sun, G
Longbottom, ER
Pullen, TJ
Xavier, GDS
Rutter, GA
Leclerc, I
Item Type: Journal Article
Issue Date: 1-Jan-2010
URI: http://hdl.handle.net/10044/1/54047
DOI: https://dx.doi.org/10.2337/db08-0868
ISSN: 0012-1797
Publisher: AMER DIABETES ASSOC
Start Page: 153
End Page: 160
Journal / Book Title: DIABETES
Volume: 59
Issue: 1
Copyright Statement: © 2010 American Diabetes Association Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.
Sponsor/Funder: Medical Research Council (MRC)
Funder's Grant Number: G0401641
Keywords: Science & Technology
Life Sciences & Biomedicine
Endocrinology & Metabolism
ENDOCRINOLOGY & METABOLISM
STIMULATED INSULIN-SECRETION
PYRUVATE-KINASE GENE
GLUCOSE STIMULATION
TRANSCRIPTION
OBESITY
YOUNG
MLX
AMP
DYSFUNCTION
PROMOTER
Animals
Aryl Hydrocarbon Receptor Nuclear Translocator
Cell Culture Techniques
Chromatin
DNA Primers
Gene Expression Regulation
Glucose
Insulin-Secreting Cells
Male
Mice
Mice, Inbred Strains
Nuclear Proteins
Oligonucleotide Array Sequence Analysis
Polymerase Chain Reaction
Promoter Regions, Genetic
RNA
Rats
Transcription Factors
Transfection
11 Medical And Health Sciences
Publication Status: Published
Appears in Collections:Department of Medicine
Faculty of Medicine



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