A Key Role for the Endothelium in NOD1 Mediated Vascular Inflammation: Comparison to TLR4 Responses

Title: A Key Role for the Endothelium in NOD1 Mediated Vascular Inflammation: Comparison to TLR4 Responses
Author(s): Gatheral, T
Reed, DM
Moreno, L
Gough, PJ
Votta, BJ
Sehon, CA
Rickard, DJ
Bertin, J
Lim, E
Nicholson, AG
Mitchell, JA
Item Type: Journal Article
Publication Date: 1-Aug-2012
URI: http://hdl.handle.net/10044/1/54009
DOI: https://dx.doi.org/10.1371/journal.pone.0042386
ISSN: 1932-6203
Publisher: PUBLIC LIBRARY SCIENCE
Journal / Book Title: PLOS ONE
Volume: 7
Issue: 8
Copyright Statement: ©2012 Gatheral et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Sponsor/Funder: British Heart Foundation
Funder's Grant Number: FS/09/017/26810
Keywords: Science & Technology
Multidisciplinary Sciences
Science & Technology - Other Topics
MULTIDISCIPLINARY SCIENCES
TOLL-LIKE RECEPTOR
NUCLEOTIDE OLIGOMERIZATION DOMAIN
PATTERN-RECOGNITION RECEPTORS
NITRIC-OXIDE SYNTHASE
KAPPA-B ACTIVATION
SEVERE SEPSIS
ORGAN-CULTURE
SMOOTH-MUSCLE
SEPTIC SHOCK
INDUCTION
Animals
Cells, Cultured
Endothelial Cells
Endothelium, Vascular
Gram-Negative Bacteria
Humans
MAP Kinase Kinase Kinases
MAP Kinase Signaling System
Male
Muscle, Smooth, Vascular
NF-kappa B
Nod1 Signaling Adaptor Protein
Peptidoglycan
Rats
Rats, Sprague-Dawley
Receptor-Interacting Protein Serine-Threonine Kinase 2
Toll-Like Receptor 4
Vasculitis
p38 Mitogen-Activated Protein Kinases
Muscle, Smooth, Vascular
Endothelium, Vascular
Cells, Cultured
Endothelial Cells
Animals
Humans
Rats
Rats, Sprague-Dawley
Gram-Negative Bacteria
Vasculitis
MAP Kinase Kinase Kinases
p38 Mitogen-Activated Protein Kinases
Peptidoglycan
NF-kappa B
MAP Kinase Signaling System
Male
Toll-Like Receptor 4
Nod1 Signaling Adaptor Protein
Receptor-Interacting Protein Serine-Threonine Kinase 2
MD Multidisciplinary
General Science & Technology
Publication Status: Published
Article Number: ARTN e42386
Appears in Collections:National Heart and Lung Institute
Airway Disease
Faculty of Medicine



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