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Consensus-Phenotype Integration of Transcriptomic and Metabolomic Data Implies a Role for Metabolism in the Chemosensitivity of Tumour Cells

Title: Consensus-Phenotype Integration of Transcriptomic and Metabolomic Data Implies a Role for Metabolism in the Chemosensitivity of Tumour Cells
Authors: Cavill, R
Kamburov, A
Ellis, JK
Athersuch, TJ
Blagrove, MSC
Herwig, R
Ebbels, TMD
Keun, HC
Item Type: Journal Article
Issue Date: 1-Mar-2011
URI: http://hdl.handle.net/10044/1/53155
DOI: https://dx.doi.org/10.1371/journal.pcbi.1001113
ISSN: 1553-734X
Publisher: PUBLIC LIBRARY SCIENCE
Journal / Book Title: PLOS COMPUTATIONAL BIOLOGY
Volume: 7
Issue: 3
Copyright Statement: © 2011 Cavill et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Sponsor/Funder: Medical Research Council (MRC)
Medical Research Council (MRC)
Funder's Grant Number: G0801056B
G0801056
Keywords: Science & Technology
Life Sciences & Biomedicine
Biochemical Research Methods
Mathematical & Computational Biology
Biochemistry & Molecular Biology
BIOCHEMICAL RESEARCH METHODS
MATHEMATICAL & COMPUTATIONAL BIOLOGY
GENE-EXPRESSION
INDUCED HEPATOTOXICITY
CANCER CELLS
RESISTANCE
PATHWAYS
CISPLATIN
CYTOTOXICITY
PROFILES
PROTEIN
IDENTIFICATION
Antineoplastic Agents
Biomarkers
Carboplatin
Cell Line, Tumor
Cisplatin
Computational Biology
Drug Screening Assays, Antitumor
False Positive Reactions
Humans
Lipoproteins
Metabolomics
Neoplasms
Oligonucleotide Array Sequence Analysis
Organoplatinum Compounds
Phenotype
Transcription, Genetic
06 Biological Sciences
08 Information And Computing Sciences
01 Mathematical Sciences
Bioinformatics
Publication Status: Published
Article Number: ARTN e1001113
Appears in Collections:Division of Surgery
Division of Cancer
Department of Medicine
Faculty of Medicine



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