Burden of diarrhea in the Eastern Mediterranean Region, 1990–2015: Findings from the Global Burden of Disease 2015 study

Title: Burden of diarrhea in the Eastern Mediterranean Region, 1990–2015: Findings from the Global Burden of Disease 2015 study
Authors: Khalil, I
El Bcheraoui, C
Charara, R
Moradi-Lakeh, M
Afshin, A
Kassebaum, NJ
Collison, M
Chew, A
Krohn, KJ
Daoud, F
Colombara, D
Foreman, KJ
Godwin, WW
Kutz, M
Mirarefin, M
Rao, PC
Reiner, R
Troeger, C
Wang, H
Abraha, HN
Abu-Elyazeed, R
Abu-Raddad, LJ
Ahmad Kiadaliri, A
Ahmadi, A
Ahmed, MB
Alam, K
Alizadeh-Navaei, R
Al-Raddadi, R
Altirkawi, KA
Alvis-Guzman, N
Anber, N
Anwari, P
Atey, TM
Avokpaho, EFGA
Bacha, U
Bazargan-Hejazi, S
Bedi, N
Bensenor, IM
Berhane, A
Bessong, PO
Beyene, AS
Bhutta, ZA
Buckle, GC
Butt, ZA
Danawi, H
Deribew, A
Djalalinia, S
Dubey, M
Endries, AY
Eshrati, B
Fereshtehnejad, SM
Fischer, F
Gebrehiwot, TT
Gugnani, HC
Hamadeh, RR
Hamidi, S
Husseini, A
James, SL
Jonas, JB
Khader, YS
Khan, EA
Khan, G
Khubchandani, J
Kissoon, N
Kopec, JA
Koyanagi, A
Kuate Defo, B
Larson, HJ
Latif, AA
Lunevicius, R
Magdy Abd El Razek, H
Magdy Abd El Razek, M
Majdzadeh, R
Majeed, A
Malekzadeh, R
Memiah, P
Memish, ZA
Mendoza, W
Mengistu, DT
Mohammed, S
Murthy, S
Ngunjiri, JW
Ogbo, FA
Pourmalek, F
Radfar, A
Rafay, A
Rahimi-Movaghar, V
Rai, RK
Ram, U
Rawaf, DL
Rawaf, S
Renzaho, AMN
Rezaei, S
Roshandel, G
Safdarian, M
Sahraian, MA
Salamati, P
Samy, AM
Sanabria, JR
Sartorius, B
Item Type: Journal Article
Abstract: Objectives: Diarrheal diseases (DD) are an important cause of disease burden, especially in children in low-income settings. DD can also impact children’s potential livelihood through growth faltering, cognitive impairment, and other sequelae. Methods: As part of the Global Burden of Disease study, we estimated DD burden, and the burden attributable to specific risk factors and etiologies, in the Eastern Mediterranean Region (EMR) between 1990 and 2015. We calculated disability-adjusted life-years (DALYs)—the sum of years of life lost and years lived with disability—for both sexes and all ages. Results: We estimate that over 103,692 diarrhea deaths occurred in the EMR in 2015 (95% uncertainty interval: 87,018–124,692), and the mortality rate was 16.0 deaths per 100,000 persons (95% UI: 13.4–19.2). The majority of these deaths occurred in children under 5 (63.3%) (65,670 deaths, 95% UI: 53,640–79,486). DALYs per 100,000 ranged from 304 (95% UI 228–400) in Kuwait to 38,900 (95% UI 25,900–54,300) in Somalia. Conclusions: Our findings will guide evidence-based health policy decisions for interventions to achieve the ultimate goal of reducing the DD burden.
Issue Date: 1-May-2018
Date of Acceptance: 28-Jun-2017
ISSN: 1661-8556
Publisher: Springer
Start Page: 109
End Page: 121
Journal / Book Title: International Journal of Public Health
Volume: 63
Issue: Suppl. 1
Copyright Statement: © 2017 The Author(s). Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
Keywords: 1117 Public Health And Health Services
Public Health
Publication Status: Published
Online Publication Date: 2017-08-03
Appears in Collections:Faculty of Medicine
Epidemiology, Public Health and Primary Care

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