Regulation of sleep homeostasis by sexual arousal.

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Title: Regulation of sleep homeostasis by sexual arousal.
Author(s): Beckwith, EJ
Geissmann, Q
French, AS
Gilestro, GF
Item Type: Journal Article
Abstract: In all animals, sleep pressure is under continuous tight regulation. It is universally accepted that this regulation arises from a two-process model, integrating both a circadian and a homeostatic controller. Here we explore the role of environmental social signals as a third, parallel controller of sleep homeostasis and sleep pressure. We show that, in Drosophila melanogaster males, sleep pressure after sleep deprivation can be counteracted by raising their sexual arousal, either by engaging the flies with prolonged courtship activity or merely by exposing them to female pheromones.
Publication Date: 12-Sep-2017
Date of Acceptance: 29-Aug-2017
URI: http://hdl.handle.net/10044/1/50544
DOI: https://dx.doi.org/10.7554/eLife.27445
ISSN: 2050-084X
Publisher: eLife Sciences Publications Ltd
Journal / Book Title: eLife
Volume: 6
Copyright Statement: © 2017, Beckwith et al. This article is distributed under the terms of the Creative Commons Attribution License permitting unrestricted use and redistribution provided that the original author and source are credited.
Sponsor/Funder: Biotechnology and Biological Sciences Research Council (BBSRC)
Biotechnology and Biological Sciences Research Cou
European Molecular Biology Organization
European Research Council
Funder's Grant Number: BB/M003930/1
4020012831
ALTF 57-2014
project 705930 - SEX_FIGHT_SLEEP
Keywords: D. melanogaster
computational biology
neuroscience
systems biology
Publication Status: Published online
Article Number: e27445
Appears in Collections:Faculty of Natural Sciences



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