A cluster randomised feasibility study of an adolescent incentive intervention to increase uptake of HPV vaccination.

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Title: A cluster randomised feasibility study of an adolescent incentive intervention to increase uptake of HPV vaccination.
Author(s): Forster, AS
Cornelius, V
Rockliffe, L
Marlow, LA
Bedford, H
Waller, J
Item Type: Journal Article
Abstract: BACKGROUND: Uptake of human papillomavirus (HPV) vaccination is suboptimal among some groups. We aimed to determine the feasibility of undertaking a cluster randomised controlled trial (RCT) of incentives to improve HPV vaccination uptake by increasing consent form return. METHODS: An equal-allocation, two-arm cluster RCT design was used. We invited 60 London schools to participate. Those agreeing were randomised to either a standard invitation or incentive intervention arm, in which Year 8 girls had the chance to win a £50 shopping voucher if they returned a vaccination consent form, regardless of whether consent was provided. We collected data on school and parent participation rates and questionnaire response rates. Analyses were descriptive. RESULTS: Six schools completed the trial and only 3% of parents opted out. The response rate was 70% for the girls' questionnaire and 17% for the parents'. In the intervention arm, 87% of girls returned a consent form compared with 67% in the standard invitation arm. The proportion of girls whose parents gave consent for vaccination was higher in the intervention arm (76%) than the standard invitation arm (61%). CONCLUSIONS: An RCT of an incentive intervention is feasible. The intervention may improve vaccination uptake but a fully powered RCT is needed.British Journal of Cancer advance online publication: 22 August 2017; doi:10.1038/bjc.2017.284 www.bjcancer.com.
Publication Date: 22-Aug-2017
Date of Acceptance: 27-Jul-2017
URI: http://hdl.handle.net/10044/1/50377
DOI: https://dx.doi.org/10.1038/bjc.2017.284
ISSN: 0007-0920
Publisher: Cancer Research UK
Start Page: 1121
End Page: 1127
Journal / Book Title: British Journal of Cancer
Volume: 117
Copyright Statement: This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
Keywords: 1112 Oncology And Carcinogenesis
Oncology & Carcinogenesis
Publication Status: Published online
Appears in Collections:Faculty of Medicine
Epidemiology, Public Health and Primary Care



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