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Oncological challenges for an ageing population living with HIV

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Title: Oncological challenges for an ageing population living with HIV
Authors: Dalla Pria, A
Merchant, S
Bower, M
Item Type: Journal Article
Abstract: mprovements in survivalandchanging patternsof transmission mean thatthe population of people living with HIV (PLWH) is ageing. Increasing age is a risk factor for many varieties of cancer, including most non-AIDS-defining malignancies. Moreover, the premature ageing described in PLWH and the development of cancer share many molecular features. As a consequence, there has been a dramatic increase in the number of PLWH who are diagnosed with cancer. The treatment of older HIV-positive patients with cancer requires careful attention to details. It is particularly important to take into account comorbidities, pharmacological drug interactions, and opportunistic infection prophylaxiswhendecidingonclinicalmanagementforthesepatients.Thus,cancerinthe ageing population living with HIV poses many challenges for both HIV physicians and oncologists.
Issue Date: 1-Jun-2017
Date of Acceptance: 16-Feb-2017
URI: http://hdl.handle.net/10044/1/49513
DOI: https://dx.doi.org/10.1097/QAD.0000000000001449
ISSN: 0269-9370
Publisher: Wolters Kluwer Health
Start Page: S185
End Page: S189
Journal / Book Title: AIDS
Volume: 31
Copyright Statement: © 2017 Wolters Kluwer Health, Inc. All rights reserved.
Keywords: Science & Technology
Life Sciences & Biomedicine
Immunology
Infectious Diseases
Virology
cancer
HIV
Kaposi sarcoma
lymphoma
COMBINATION ANTIRETROVIRAL THERAPY
HUMAN-IMMUNODEFICIENCY-VIRUS
UNITED-STATES
KAPOSIS-SARCOMA
CANCER-RISK
GENERAL-POPULATION
LUNG-CANCER
OLDER
CHEMOTHERAPY
HALLMARKS
06 Biological Sciences
11 Medical And Health Sciences
17 Psychology And Cognitive Sciences
Publication Status: Published
Appears in Collections:Division of Surgery
Division of Cancer
Faculty of Medicine



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