Differential effect of visual motion adaption upon visual cortical excitability

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Title: Differential effect of visual motion adaption upon visual cortical excitability
Author(s): Lubeck, AJA
Van Ombergen, A
Ahmad, H
Bos, JE
Wuyts, FL
Bronstein, AM
Arshad, Q
Item Type: Journal Article
Abstract: The objectives of this study were 1) to probe the effects of visual motion adaptation on early visual and V5/MT cortical excitability and 2) to investigate whether changes in cortical excitability following visual motion adaptation are related to the degree of visual dependency, i.e., an overreliance on visual cues compared with vestibular or proprioceptive cues. Participants were exposed to a roll motion visual stimulus before, during, and after visual motion adaptation. At these stages, 20 transcranial magnetic stimulation (TMS) pulses at phosphene threshold values were applied over early visual and V5/MT cortical areas from which the probability of eliciting a phosphene was calculated. Before and after adaptation, participants aligned the subjective visual vertical in front of the roll motion stimulus as a marker of visual dependency. During adaptation, early visual cortex excitability decreased whereas V5/MT excitability increased. After adaptation, both early visual and V5/MT excitability were increased. The roll motion-induced tilt of the subjective visual vertical (visual dependence) was not influenced by visual motion adaptation and did not correlate with phosphene threshold or visual cortex excitability. We conclude that early visual and V5/MT cortical excitability is differentially affected by visual motion adaptation. Furthermore, excitability in the early or late visual cortex is not associated with an increase in visual reliance during spatial orientation. Our findings complement earlier studies that have probed visual cortical excitability following motion adaptation and highlight the differential role of the early visual cortex and V5/MT in visual motion processing.
Publication Date: 29-Nov-2016
Date of Acceptance: 29-Nov-2016
URI: http://hdl.handle.net/10044/1/49369
DOI: https://dx.doi.org/10.1152/jn.00655.2016
ISSN: 0022-3077
Publisher: American Physiological Society
Start Page: 903
End Page: 909
Journal / Book Title: Journal of Neurophysiology
Volume: 117
Issue: 3
Copyright Statement: © 2017 the American Physiological Society.
Keywords: Science & Technology
Life Sciences & Biomedicine
Neurosciences
Physiology
Neurosciences & Neurology
visual motion adaptation
early visual cortex
V5/MT
visual dependency
cortical excitability
transcranial magnetic stimulation
TRANSCRANIAL MAGNETIC STIMULATION
CORTEX EXCITABILITY
VESTIBULAR FAILURE
POSTURAL CONTROL
SELF-MOTION
PERCEPTION
AWARENESS
VERTIGO
AREA
ADAPTATION
V5/MT
cortical excitability
early visual cortex
transcranial magnetic stimulation
visual dependency
visual motion adaptation
11 Medical And Health Sciences
17 Psychology And Cognitive Sciences
Neurology & Neurosurgery
Publication Status: Published
Embargo Date: 2018-11-29
Appears in Collections:Department of Medicine
Faculty of Medicine



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