A review of transition experiences in perinatally and behaviourally acquired HIV-1 infection; same, same but different?

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Title: A review of transition experiences in perinatally and behaviourally acquired HIV-1 infection; same, same but different?
Authors: Lam, PK
Fidler, S
Foster, C
Item Type: Journal Article
Abstract: Introduction: Despite sharing common psychosocial and developmental experiences, adolescents living with perinatally and behaviourally acquired HIV-1 infection are different in terms of timing of HIV infection and developmental stage at infection. Therefore, it is of interest to identify similarities and differences between these two groups of adolescents living with HIV in their experiences, facilitators and barriers during the transition process. Methods: A detailed literature search of peer-reviewed published papers was conducted on PubMed to identify relevant original research or viewpoints published up to September 2016. Conference abstracts and other unpublished data sources were not included. Results: Existing published literature, mainly using qualitative methods, explores the transition from paediatric to adult healthcare provision, as experienced by these two groups of young people. Reports highlight the variation and similarities in their experiences and challenges of transition. Findings from the USA and Europe predominate, while experience from Africa and Asia is lacking, despite the importance of these regions in the global epidemic. Conclusions: Published transition data remain limited, and there are few studies focusing on behaviourally infected adolescents and key population groups (e.g. adolescents who use drugs, lesbian/gay/transgender individuals). Robust definitions of the transition process and standardized outcome measures are required to facilitate cross-study and geographic comparisons.
Issue Date: 16-May-2017
Date of Acceptance: 15-Feb-2017
ISSN: 1758-2652
Publisher: BioMed Central
Journal / Book Title: Journal of the International AIDS Society
Volume: 20
Copyright Statement: © 2017 Lam PK et al; licensee International AIDS Society. This is an Open Access article distributed under the terms of the Creative Commons Attribution 3.0 Unported (CC BY 3.0) License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Sponsor/Funder: Imperial College Healthcare NHS Trust- BRC Funding
Funder's Grant Number: RDA02 79560
Keywords: Science & Technology
Life Sciences & Biomedicine
Infectious Diseases
Transition experience
young people
modes of infection
1199 Other Medical And Health Sciences
Publication Status: Published
Article Number: ARTN 21506
Appears in Collections:Department of Medicine
Faculty of Medicine

This item is licensed under a Creative Commons License Creative Commons