The added value of small-molecule chirality in technological applications

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Title: The added value of small-molecule chirality in technological applications
Author(s): Brandt, JR
Salerno, F
Fuchter, MJ
Item Type: Journal Article
Abstract: Chirality is a fundamental symmetry property; chiral objects, such as chiral small molecules, exist as a pair of non-superimposable mirror images. Although small-molecule chirality is routinely considered in biologically focused application areas (such as drug discovery and chemical biology), other areas of scientific development have not considered small-molecule chirality to be central to their approach. In this Review, we highlight recent research in which chirality has enabled advancement in technological applications. We showcase examples in which the presence of small-molecule chirality is exploited in ways beyond the simple interaction of two different chiral molecules; this can enable the detection and emission of chiral light, help to control molecular motion, or provide a means to control electron spin and bulk charge transport. Thus, we demonstrate that small-molecule chirality is a highly promising avenue for a wide range of technologically oriented scientific endeavours.
Publication Date: 7-Jun-2017
Date of Acceptance: 8-May-2017
URI: http://hdl.handle.net/10044/1/48462
DOI: https://dx.doi.org/10.1038/s41570-017-0045
ISSN: 2397-3358
Journal / Book Title: Nature Reviews Chemistry
Volume: 1
Copyright Statement: © 2017 Macmillan Publishers Limited, part of Springer Nature. All rights reserved.
Sponsor/Funder: Engineering & Physical Science Research Council (EPSRC)
Engineering & Physical Science Research Council (EPSRC)
Funder's Grant Number: EP/L014580/1
EP/P000525/1
Publication Status: Published
Article Number: 0045
Appears in Collections:Chemistry
Faculty of Natural Sciences



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