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Results 1-10 of 31
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Issue DateTitleAuthor(s)
16-Jan-2018Corrigendum: Inhibitor selectivity for cyclin-dependent kinase 7: a structural, thermodynamic, and modelling studyHazel, P; Kroll, SHB; Bondke, A; Barbazanges, M; Patel, H, et al
20-Aug-2016ICEC0942, an orally bioavailable selective inhibitor of CDK7 for breast cancerAli, S; Patel, H; Periyasamy, M; Bondke, A; Slafer, BW, et al
25-Apr-2017Competition-based, quantitative chemical proteomics in breast cancer cells identifies new target profiles for sulforaphaneClulow, JA; Storck, EM; Lanyon-Hogg, T; Kalesh, KA; Jones, LH, et al
8-Jun-2017Dynamic protein acylation: new substrates, mechanisms and drug targetsLanyon-Hogg, T; Faronato, M; Serwa, RA; Tate, EW; Cancer Research UK, et al
6-Dec-2013Mechanistic and Chiroptical Studies on the Desulfurization of Epidithiodioxopiperazines Reveal Universal Retention of Configuration at the Bridgehead Carbon AtomsCherblanc, FL; Lo, Y-P; Herrebout, WA; Bultinck, P; Rzepa, HS, et al
15-Mar-2018ICEC0942, an orally bioavailable selective inhibitor of CDK7 for cancer treatmentAli, S; Patel, H; Periyasamy, M; Sava, G; Bondke, A, et al
15-Mar-2017Identification of diaminoquinazoline histone lysine methyltransferase structure activity relationships that allow for segregation of human G9a inhibition and anti-Plasmodium activitySundriyal, S; Chen, P; Lubin, A; Lueg, G; Lu, F, et al
11-Jun-2014Nicastrin and Notch4 drive endocrine therapy resistance and epithelial to mesenchymal transition in MCF7 breast cancer cellsLombardo, Y; Faronato, M; Filipovic, A; Vircillo, V; Magnani, L, et al
30-Jan-2017Thienopyrimidinone based sirtuin-2 (SIRT2)-selective inhibitors bind in the ligand induced 'selectivity pocket'.Sundriyal, S; Moniot, S; Mahmud, Z; Yao, S; Di Fruscia, P, et al
10-Feb-2016Synthesis and characterisation of 5-acyl-6,7-dihydrothieno[3,2-c]pyridine inhibitors of Hedgehog acyltransferaseLanyon-Hogg, T; Masumoto, N; Bodakh, G; Konitsiotis, AD; Thinon, E, et al