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Hepatocellular carcinoma: an evolving challenge in viral hepatitis and HIV coinfection

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Title: Hepatocellular carcinoma: an evolving challenge in viral hepatitis and HIV coinfection
Authors: Pinato, DJ
Dalla Pria, A
Sharma, R
Bower, M
Item Type: Journal Article
Abstract: Liver-related morbidity and mortality is expanding in people living with HIV. Hepatocellular carcinoma (HCC), the third most lethal malignancy on a global scale, is a dominant complication of chronic liver disease and cirrhosis in patients with coexisting hepatitis. HIV infection further complicates the clinical heterogeneity of HCC, posing concurrent challenges stemming from the underlying immunological status of the patients and the ongoing need for combined antiretroviral therapy. In this article, we review the multiple clinical implications that characterize the multidisciplinary management of HCC in the context of HIV infection.
Issue Date: 13-Mar-2017
Date of Acceptance: 16-Jan-2017
URI: http://hdl.handle.net/10044/1/45929
DOI: https://dx.doi.org/10.1097/QAD.0000000000001422
ISSN: 0269-9370
Publisher: LIPPINCOTT WILLIAMS & WILKINS
Start Page: 603
End Page: 611
Journal / Book Title: AIDS
Volume: 31
Issue: 5
Copyright Statement: © 2017 Wolters Kluwer Health, Inc. This is a non-final version of an article published in final form in AIDS Issue: Volume 31(5), 13 March 2017, p 603–611 available at https://dx.doi.org/10.1097/QAD.0000000000001422
Keywords: Science & Technology
Life Sciences & Biomedicine
Immunology
Infectious Diseases
Virology
hepatocellular carcinoma
HIV
management
prognosis
HUMAN-IMMUNODEFICIENCY-VIRUS
RANDOMIZED CONTROLLED-TRIAL
C VIRUS
B-VIRUS
INFECTED PATIENTS
LIVER-DISEASE
ANTIRETROVIRAL THERAPY
SUSCEPTIBILITY LOCUS
CLINICAL MANAGEMENT
IMMUNE ACTIVATION
06 Biological Sciences
11 Medical And Health Sciences
17 Psychology And Cognitive Sciences
Publication Status: Published
Appears in Collections:Division of Surgery
Division of Cancer
Faculty of Medicine



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