A complicated multisystem flare of systemic lupus erythematosus during pregnancy.

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Title: A complicated multisystem flare of systemic lupus erythematosus during pregnancy.
Authors: Webster, P
Nelson-Piercy, C
Lightstone, L
Item Type: Journal Article
Abstract: We report a case of systemic lupus erythematosus (SLE) in a young woman who became pregnant amid a severe flare. She continued to have active disease in the face of aggressive treatments complicated by several side effects of immunosuppressive drugs including recurrent sepsis and gestational diabetes. Her fetus was at risk for congenital heart block during the second and third trimesters. Despite an extremely guarded prognosis, she delivered a healthy baby girl. This case highlights the complexities of SLE management during pregnancy. We discuss the therapeutic options available in pregnancy, and highlight the importance of cross-specialty multidisciplinary care in these women.
Issue Date: 8-Feb-2017
Date of Acceptance: 23-Jan-2017
URI: http://hdl.handle.net/10044/1/45559
DOI: https://dx.doi.org/10.1136/bcr-2016-217546
ISSN: 1757-790X
Publisher: BMJ Publishing Group
Journal / Book Title: BMJ Case Reports
Volume: 2017
Copyright Statement: © 2017 BMJ Publishing Group. All rights reserved. For permission to reuse any of this content visit http://group.bmj.com/group/rights-licensing/permissions. This article has been accepted for publication in BMJ Case Reports following peer review. The definitive copyedited, typeset version Webster P, et al. BMJ Case Rep 2017. doi:10.1136/bcr-2016-217546 is available online at: https://dx.doi.org/10.1136/bcr-2016-217546
Sponsor/Funder: Imperial College Healthcare NHS Trust- BRC Funding
Funder's Grant Number: RDA04 79560
Keywords: Adult
Diabetes, Gestational
Immunosuppressive Agents
Lupus Erythematosus, Systemic
Pregnancy Complications
Pregnancy Outcome
Publication Status: Published
Conference Place: England
Appears in Collections:Department of Medicine
Faculty of Medicine

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