Dataset of the human homologues and orthologues of lipid-metabolic genes identified as DAF-16 targets and their roles in lipid and energy metabolism

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Title: Dataset of the human homologues and orthologues of lipid-metabolic genes identified as DAF-16 targets and their roles in lipid and energy metabolism
Authors: Fan, LY
Saavedra Garcia, P
Lam, EW
Item Type: Journal Article
Abstract: The data presented in this article are related to the review article entitled ‘Unravelling the role of fatty acid metabolism in cancer through the FOXO3-FOXM1 axis’ (Saavedra-Garcia et al., 2017) [24]. Here, we have matched the DAF-16/FOXO3 downstream genes with their respective human orthologues and reviewed the roles of these targeted genes in FA metabolism. The list of genes listed in this article are precisely selected from literature reviews based on their functions in mammalian FA metabolism. The nematode Caenorhabditis elegans gene orthologues of the genes are obtained from WormBase, the online biological database of C. elegans. This dataset has not been uploaded to a public repository yet.
Issue Date: 8-Mar-2017
Date of Acceptance: 28-Feb-2017
ISSN: 2352-3409
Publisher: Elsevier
Start Page: 606
End Page: 610
Journal / Book Title: Data in Brief
Volume: 11
Copyright Statement: © 2017 The Authors. Published by E lsevier Inc. This is an open access article under the CC BY license (
Sponsor/Funder: Medical Research Council (MRC)
Imperial College Trust
Funder's Grant Number: MR/N012097/1
Keywords: ACAA2, Acetyl-CoA acetyltransferase 2
ACACA, Acetyl-CoA carboxylase
ACAD8, Acyl-CoA dehydrogenase family member 8
ACADM, Acyl-CoA dehydrogenase C4 to C12 straight chain
ACOX, Acyl-CoA oxidase
ACSL3/4, Acyl-CoA synthetase long-chain family member 3/4
ACSS, Acyl-CoA synthetase short-chain family member
CPT2, Carnitine palmitoyltransferase II
Caenorhabditis elegans
DAG, Diacylglycerol
DGAT, Diacylglycerol O-acyltransferase
ECHS1, Short-chain enoyl-CoA hydratase 1
ELOVL1, Elongation of very long chain fatty acids protein 1
FA, fatty acid
FADS2, Fatty acid desaturase 2
FASN, Fatty acid synthase
FATP4, Fatty acid transport protein 4
FOX, Forkhead box
HADH, Hydroxyacyl-coenzyme A dehydrogenase
HADHA, Hydroxyacyl-CoA dehydrogenase/3-Ketoacyl-CoA thiolase/Enoyl-CoA hydratase, alpha subunit
LCFA, Long chain fatty acid
Lipid metabolism
MLYCD, Malonyl-CoA decarboxylase
MOGAT1/2, Monoacylglycerol O-acyltransferase 1/2
PNPLA, patatin like phospholipase domain containing
PUFA, polyunsaturated fatty acid
SCD1/5, Stearoyl-CoA desaturase 1/5
TAG, triacylglycerol
TCA, Tricarboxylic acid
VLCFA, Very long chain fatty acid.
Publication Status: Published
Appears in Collections:Division of Surgery
Division of Cancer
Faculty of Medicine

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