An extended 3D whole-heart myocardial first-pass perfusion sequence: alternate-cycle views with isotropic and high-resolution imaging

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Title: An extended 3D whole-heart myocardial first-pass perfusion sequence: alternate-cycle views with isotropic and high-resolution imaging
Authors: Fair, M
Gatehouse, P
DiBella, EVR
Chen, L
Firmin, DN
Item Type: Conference Paper
Abstract: Simultaneously optimising parameters such as LV cover- age, image resolution and contrast sensitivity is difficult in first-pass perfusion (FPP). 3D FPP shows potential (1) to improve coverage, but “ whole-heart ” coverage demands high acceleration forcing compromises such as loss of spatial resolution. 2D FPP shows high diagnostic ability with more slices distributed over alternate-RR cycles (2), relaxing acceleration requirements. This work proposes that 3D FPP could interleave two strategies with different 3D parameters in alternate cycles, in sum approaching the full set of desired FPP properties. This work also aims to improve sp ecificity against artefacts by imaging the same myocardium with two different interleaved 3D scans (distinct from reformatting a single 3D FPP scan). Similar confirmation strategies are often used in CMR, such as repetition with swapped phase- encode direction in late-enhancement imaging.
Issue Date: 27-Jan-2016
Date of Acceptance: 27-Jan-2016
ISSN: 1532-429X
Publisher: BioMed Central
Journal / Book Title: Journal of Cardiovascular Magnetic Resonance
Volume: 18
Issue: Suppl. 1
Copyright Statement: © Fair et al. 2016. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.
Sponsor/Funder: British Heart Foundation
British Heart Foundation
Royal Brompton & Harefield NHS Foundation Trust
Funder's Grant Number: FS/04/071
6004 D Firmin Research Associa
Conference Name: Society for Cardiovascular Magnetic Resonance
Keywords: Nuclear Medicine & Medical Imaging
1102 Cardiovascular Medicine And Haematology
Publication Status: Published
Start Date: 2016-01-27
Finish Date: 2016-01-30
Conference Place: Los Angeles, CA
Open Access location:
Appears in Collections:National Heart and Lung Institute

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