Atopic dermatitis and respiratory allergy: what is the link

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Title: Atopic dermatitis and respiratory allergy: what is the link
Authors: Belgrave, DC
Simpson, A
Buchan, IE
Custovic, A
Item Type: Journal Article
Abstract: Understanding the aetiology and progression of atopic dermatitis and respiratory allergy may elucidate early preventative and management strategies aimed towards reducing the global burden of asthma and allergic disease. In this article, we review the current opinion concerning the link between atopic dermatitis and the subsequent progression of respiratory allergies during childhood and into early adolescence. Advances in machine learning and statistical methodology have facilitated the discovery of more refined definitions of phenotypes for identifying biomarkers. Understanding the role of atopic dermatitis in the development of respiratory allergy may ultimately allow us to determine more effective treatment strategies, thus reducing the patient and economic burden associated with these conditions.
Issue Date: 28-Sep-2015
Date of Acceptance: 1-Sep-2015
URI: http://hdl.handle.net/10044/1/42834
DOI: https://dx.doi.org/10.1007/s13671-015-0121-6
ISSN: 2162-4933
Publisher: Springer Verlag (Germany)
Start Page: 221
End Page: 227
Journal / Book Title: Current Dermatology Reports
Volume: 4
Issue: 4
Copyright Statement: © Springer Science+Business Media New York 2015. This is an open access article available under the CC-BY licence 4.0 (https://creativecommons.org/licenses/by/4.0/)
Sponsor/Funder: Medical Research Council (MRC)
Funder's Grant Number: MR/M015181/1
Keywords: Asthma
Atopic dermatitis
Biomarker identification
Dermatology
Respiratory allergy
Review
Statistical machine learning
Stratified and personalised medicine strategies
Publication Status: Published
Conference Place: United States
Appears in Collections:Department of Medicine
Faculty of Medicine



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