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MetaboSignal, a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways

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Title: MetaboSignal, a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways
Authors: Rodriguez Martinez, A
Ayala, R
Posma, JM
Neves, AL
Gauguier, D
Nicholson, JK
Dumas, ME
Item Type: Journal Article
Abstract: MetaboSignal is an R package that allows merging metabolic and signaling pathways reported in the Kyoto Encyclopaedia of Genes and Genomes (KEGG). It is a network-based approach designed to navigate through topological relationships between genes (signaling- or metabolic-genes) and metabolites, representing a powerful tool to investigate the genetic landscape of metabolic phenotypes.
Issue Date: 5-Dec-2016
Date of Acceptance: 3-Nov-2016
URI: http://hdl.handle.net/10044/1/42300
DOI: https://dx.doi.org/10.1093/bioinformatics/btw697
ISSN: 1367-4803
Publisher: Oxford University Press
Start Page: 773
End Page: 775
Journal / Book Title: Bioinformatics
Volume: 33
Issue: 5
Copyright Statement: © The Author 2016. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords: Bioinformatics
01 Mathematical Sciences
06 Biological Sciences
08 Information And Computing Sciences
Publication Status: Published
Appears in Collections:Division of Surgery
Department of Medicine
Faculty of Medicine



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